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Many cellular networks rely on the regulated transport of their components to transduce extracellular information into precise intracellular signals. The dynamics of these networks is typically described in terms of compartmentalized…

Subcellular Processes · Quantitative Biology 2011-11-18 Jose M. G. Vilar , Leonor Saiz

The biological cell exhibits a fantastic range of behaviors, but ultimately these are governed by a handful of physical and chemical principles. Here we explore simple theory, known for decades and based on the simple thermodynamics of…

Biomolecules · Quantitative Biology 2020-03-25 Daniel M. Zuckerman

The dynamic interplay between collective cell movement and the various molecules involved in the accompanying cell signalling mechanisms plays a crucial role in many biological processes including normal tissue development and pathological…

Cell Behavior · Quantitative Biology 2016-07-20 Pia Domschke , Dumitru Trucu , Alf Gerisch , Mark A. J. Chaplain

Transport and dispersion of active particles in structured environments such as corrugated channels and porous media are important for the understanding of both natural and engineered active systems. Owing to their continuous…

Soft Condensed Matter · Physics 2024-10-16 Zhiwei Peng

Flux of rigid or soft particles (such as drops, vesicles, red blood cells, etc.) in a channel is a complex function of particle concentration, which depends on the details of induced dissipation and suspension structure due to hydrodynamic…

Active adaptive matter has attracted considerable interest due to its rich, largely unexplained dynamics and its relevance to a wide range of synthetic and biological materials. An important subclass of such systems consists of active…

Soft Condensed Matter · Physics 2026-02-05 William G. C. Oropesa , P. de Castro , Hartmut Löwen , Danilo B. Liarte

Motility is a fundamental survival strategy of bacteria to navigate porous environments. Swimming cells thrive in quiescent wetlands and sediments at the bottom of the marine water column, where they mediate many essential biogeochemical…

Soft Condensed Matter · Physics 2022-01-11 Amin Dehkharghani , Nicolas Waisbord , Jeffrey S. Guasto

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

The ability of semipermeable membranes to selectively impede the transport of undesirable solutes is key to many applications. Yet, obtaining a systematic understanding of how membrane structure affects selectivity remains elusive due to…

Soft Condensed Matter · Physics 2020-01-03 Hessam Malmir , Razi Epsztein , Menachem Elimelech , Amir Haji-Akbari

In the cellular phenomena of cytoplasmic streaming, molecular motors carrying cargo along a network of microtubules entrain the surrounding fluid. The piconewton forces produced by individual motors are sufficient to deform long…

Soft Condensed Matter · Physics 2021-01-20 David B. Stein , Gabriele De Canio , Eric Lauga , Michael J. Shelley , Raymond E. Goldstein

The movement of organisms and cells can be governed by occasional long distance runs, according to an approximate L\'evy walk. For T cells migrating through chronically-infected brain tissue, runs are further interrupted by long pauses, and…

Biological Physics · Physics 2020-03-06 Gissell Estrada-Rodriguez , Heiko Gimperlein , Kevin J. Painter , Jakub Stocek

The compartmental model is a basic tool for studying signal propagation in neurons, and, if the model parameters are adequately defined, it can also be of help in the study of electrical or fluid transport. Here we show that the input…

Cell Behavior · Quantitative Biology 2007-05-23 E. Louis C. Degli Esposti Boschi G. J. Ortega E. Fernandez

We consider model of a complex particle that consists of a rigid shell and a nucleus with spatial asymmetric interaction. The particle's dynamics with the nucleus driven by a periodic excitation is considered. It is shown that…

Chaotic Dynamics · Physics 2007-05-23 Sergey Denisov

The effect of curvature and how it induces and enhances the transport of colloidal particles driven through narrow channels represent an unexplored research avenue. Here we combine experiments and simulations to investigate the dynamics of…

The correspondence between the telegraph random process and transport within a binary stochastic Markovian mixture is established. This equivalence is used to derive the distribution function for the transit length, defined as the distance…

Mathematical Physics · Physics 2024-12-30 Brian C. Kiedrowski , Emily H. Vu

We study the dynamics of quantum excitations inside macromolecules which can undergo conformational transitions. In the first part of the paper, we use the path integral formalism to rigorously derive a set of coupled equations of motion…

Soft Condensed Matter · Physics 2015-06-04 L. Boninsegna , P. Faccioli

Compartmentalization into biochemically distinct organelles constantly exchanging material is one of the hallmarks of eukaryotic cells. In the most naive picture of inter-organelle transport driven by concentration gradients, concentration…

Subcellular Processes · Quantitative Biology 2015-05-27 Serge Dmitrieff , Pierre Sens

We consider a discrete time particle model for kinetic transport on the two dimensional integer lattice. The particle can move due to advection in the $x$-direction and due to dispersion. This happens when the particle is free, but it can…

Probability · Mathematics 2015-08-04 Michel Dekking , Derong Kong , Annegreet van Opbroek

We investigate the transport dynamics of elongated particles in cellular vortical flows that undergo spatial oscillations over time. Experimental flow visualizations reveal mixed flow fields with chaotic and elliptic regions coexisting.…

Fluid Dynamics · Physics 2025-08-14 Shiyuan Hu , Xiuyuan Yang , Nan Luo , Jun Zhang , Xingkun Man

Signal transduction pathways recover a crucial role in cellular processes: they represent a connection between environmental conditions and cellular reactions. There are many pathways and they all are related to create a network. But how…

General Physics · Physics 2012-10-18 Valentina Agoni
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