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Related papers: Stretching An Anisotropic DNA

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We discuss theoretically the force F between two colloidal particles, each of them carrying one single strand DNA. The two strands are complementary only on a finite sequence of consecutive base pairs. We define an adjustment length (a few…

Biological Physics · Physics 2015-06-26 Pierre-Gilles de Gennes

Within a simple elastic theory, we study the elongation versus force characteristics of a supercoiled DNA molecule at thermal equilibrium in the regime of small supercoiling. The partition function is mapped to the path integral…

Soft Condensed Matter · Physics 2016-08-31 C. Bouchiat , M. Mezard

We consider an elastic rod model for twisted DNA in the plectonemic regime. The molecule is treated as an impenetrable tube with an effective, adjustable radius. The model is solved analytically and we derive formulas for the contact…

Biomolecules · Quantitative Biology 2009-11-13 N. Clauvelin , B. Audoly , S. Neukirch

We study the depinning of a flux line by analytical and numerical methods applied to a phenomenological equation of motion. Transverse fluctuations do not influence the critical behavior of the longitudinal component, justifying ``planar…

Condensed Matter · Physics 2009-10-22 Deniz Ertas , Mehran Kardar

Living cells provide a fluctuating, out-of-equilibrium environment in which genes must coordinate cellular function. DNA looping, which is a common means of regulating transcription, is very much a stochastic process; the loops arise from…

Biomolecules · Quantitative Biology 2015-05-18 Yih-Fan Chen , J. N. Milstein , Jens-Christian Meiners

We consider a sequence of linear hyper-elastic, inhomogeneous and fully anisotropic bodies in a reference configuration occupying a cylindrical region of height epsilon. We then study, by means of Gamma-convergence, the asymptotic behavior…

Mathematical Physics · Physics 2017-04-03 Francois Murat , Roberto Paroni

We examine the conformations of a model for under- and overwound DNA. The molecule is represented as a cylindrically symmetric elastic string subjected to a stretching force and to constraints corresponding to a specification of the link…

Soft Condensed Matter · Physics 2009-10-28 Boris Fain , Joseph Rudnick , Stellan Ostlund

A new approach to the theory of anisotropic exciton based on Fock transformation, i.e., on a stereographic projection of the momentum to the unit 4-dimensional (4D) sphere, is developed. Hyperspherical functions are used as a basis of the…

Mathematical Physics · Physics 2012-05-25 E. A. Muljarov , A. L. Yablonskii , S. G. Tikhodeev , A. E. Bulatov , Joseph L. Birman

Using theory and simulations, we carried out a first systematic characterization of DNA unzipping via nanopore translocation. Starting from partially unzipped states, we found three dynamical regimes depending on the applied force, f: (i)…

Soft Condensed Matter · Physics 2023-02-08 Antonio Suma , Vincenzo Carnevale , Cristian Micheletti

The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschke indicate the existence of a sliding process, permitting…

Biomolecules · Quantitative Biology 2007-05-23 Richard A. Neher , Ulrich Gerland

Overstretching of B-DNA is currently understood as force-induced melting. Depending on the geometry of the stretching experiment, the force threshold for the overstretching transition is around 65 or 110 pN. Although the mechanisms behind…

Biological Physics · Physics 2019-03-06 Nikos Theodorakopoulos

In this numerical study, measurements of the contact forces inside a periodic two-dimensional sheared system of soft frictional particles are reported. The distribution of normalized normal forces exhibits a gradual broadening with…

Soft Condensed Matter · Physics 2015-07-28 Jens Boberski , M. Reza Shaebani , Dietrich E. Wolf

The influence of decoherence and bonding on the linear conductance of single double-stranded DNA molecules is examined by fitting a phenomenological statistical model developed recently (EPJB {\bf 68}, 237 (2009)) to experimental results.…

Soft Condensed Matter · Physics 2010-09-30 M. Zilly , O. Ujsaghy , D. E. Wolf

Animal cells are active, contractile objects. While bioassays address the molecular characterization of cell contractility, the mechanical characterization of the active forces in cells remains challenging. Here by confronting theoretical…

Cell Behavior · Quantitative Biology 2022-09-14 Hélène Delanoë-Ayari , Nicolas Bouchonville , Marie Courçon , Alice Nicolas

Friction-induced energy dissipation impedes the performance of nanoscale devices during their relative motion. Nevertheless, an ingeniously designed structure which utilizes graphene topping can tune the friction force signal by inducing…

Nanochannels provide means for detailed experiments on the effect of confinement on biomacromolecules, such as DNA. We here introduce a model for the complete unfolding of DNA from the circular to linear configuration. Two main ingredients…

We study the nonlinear elastic response of a two-dimensional material to a localized boundary force, with the particular goal of understanding the differences observed between isotropic granular materials and those with hexagonal…

Soft Condensed Matter · Physics 2009-11-13 B. P. Tighe , J. E. S. Socolar

Single molecule studies, at constant force, of the separation of double-stranded DNA into two separated single strands may provide information relevant to the dynamics of DNA replication. At constant applied force, theory predicts that the…

In this paper we argue that the pattern of cell movements in the morphogenetic process known as convergent extension can be understood as a energy minimization process, provided the cell-cell adhesive energy has a certain kind of…

Biological Physics · Physics 2007-05-23 Mark Zajac Gerald L. Jones , James A. Glazier

Physical experiments can characterize the elastic response of granular materials in terms of macroscopic state-variables, namely volume (packing) fraction and stress, while the microstructure is not accessible and thus neglected. Here, by…

Soft Condensed Matter · Physics 2015-06-16 Nishant Kumar , Stefan Luding , Vanessa Magnanimo