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Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…

Genomics · Quantitative Biology 2018-11-28 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

DNA is a promising storage medium, but its stability and occurrence of Indel errors pose a significant challenge. The relative occurrence of Guanine(G) and Cytosine(C) in DNA is crucial for its longevity, and reverse complementary base…

Information Theory · Computer Science 2024-01-15 NallappaBhavithran G , Selvakumar R

Based on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA…

Soft Condensed Matter · Physics 2007-05-23 Ralf Metzler , Tobias Ambjoernsson

The structural flexibility of nucleic acids plays a key role in many fundamental life processes, such as gene replication and expression, DNA-protein recognition, and gene regulation. To obtain a thorough understanding of nucleic acid…

Biological Physics · Physics 2015-09-24 Lei Bao , Xi Zhang , Lei Jin , Zhi-Jie Tan

The genetic code is profoundly shaped by an origin in ancient RNA-mediated interactions, needing an extended development to reach the Standard Genetic Code (SGC). That development can serially use RNA specificities, a ribonucleopeptide…

Populations and Evolution · Quantitative Biology 2024-06-13 Michael Yarus

In this paper we present a new method of coding/decoding algorithms using Fibonacci $Q$-matrices. This method is based on the blocked message matrices. The main advantage of our model is the encryption of each message matrix with different…

Information Theory · Computer Science 2017-12-07 Nihal Taş , Sümeyra Uçar , Nihal Yilmaz Özgür , Öznur Öztunç Kaymak

The domain name system (DNS) that maps alphabetic names to numeric Internet Protocol (IP) addresses plays a foundational role for Internet communications. By default, DNS queries and responses are exchanged in unencrypted plaintext, and…

Cryptography and Security · Computer Science 2024-07-08 Minzhao Lyu , Hassan Habibi Gharakheili , Vijay Sivaraman

This communication reports the increase in fluorescence resonance energy transfer (FRET) efficiency between two laser dyes in presence of Deoxyribonucleic acid (DNA). Two types of molecular logic gates have been designed where DNA acts as…

Biological Physics · Physics 2014-08-29 D. Bhattacharjee , Dibyendu Dey , S. Chakraborty , Syed Arshad Hussain

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

This paper presents a novel method to segment/decode DNA sequences based on n-grams statistical language model. Firstly, we find the length of most DNA 'words' is 12 to 15 bps by analyzing the genomes of 12 model species. Then we design an…

Genomics · Quantitative Biology 2015-03-13 Wang Liang

In this paper, we apply dimensional analysis to study a diffusive molecular communication system that uses diffusing enzymes in the propagation environment to mitigate intersymbol interference. The enzymes bind to information molecules and…

Information Theory · Computer Science 2013-11-21 Adam Noel , Karen C. Cheung , Robert Schober

A theoretical construction of the genetic material establishes the unique and ideal character of DNA. A similar conclusion is reached for amino acids and proteins.

Other Quantitative Biology · Quantitative Biology 2014-04-16 J. -L. Sikorav , A. Braslau , A. Goldar

The recent progress in DNA sequencing will probably revolutionize the world of electronic. Hence, we went from DNA sequencing that only research centers could realize, to portable, tiny and inexpensive tools. So, it is likely that in a few…

Cryptography and Security · Computer Science 2016-06-22 Amadou Moctar Kane

A representation of the genetic code as a six-dimensional Boolean hypercube is described. This structure is the result of the hierarchical order of the interaction energies of the bases in codon-anticodon recognition. In this paper it is…

Disordered Systems and Neural Networks · Physics 2007-05-23 Miguel A. Jimenez-Montano , Carlos R. de la Mora-Basanez , Thorsten Poeschel

We consider error-correcting coding for deoxyribonucleic acid (DNA)-based storage using nanopore sequencing. We model the DNA storage channel as a sampling noise channel where the input data is chunked into $M$ short DNA strands, which are…

Information Theory · Computer Science 2024-06-21 Lorenz Welter , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

Complex systems with tightly coadapted parts frequently appear in living systems and are difficult to account for through Darwinian evolution, that is random variation and natural selection, if the constituent parts are independently coded…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 John F. McGowan , Ph. D

Information theoretic analysis of genetic languages indicates that the naturally occurring 20 amino acids and the triplet genetic code arose by duplication of 10 amino acids of class-II and a doublet genetic code having codons NNY and…

Genomics · Quantitative Biology 2007-05-23 Apoorva Patel

Molecular communication is a novel approach for data transmission between miniaturized devices, especially in contexts where electrical signals are to be avoided. The communication is based on sending molecules (or other particles) at nano…

Emerging Technologies · Computer Science 2023-08-08 Max Bartunik , Jens Kirchner , Oliver Keszocze

In the literature there exists analytical expressions for the probability of a receiver decoding a transmitted source message that has been encoded using random linear network coding. In this work, we look into the probability that the…

Information Theory · Computer Science 2022-03-08 Jessica Claridge , Ioannis Chatzigeorgiou

Synthesis of DNA molecules offers unprecedented advances in storage technology. Yet, the microscopic world in which these molecules reside induces error patterns that are fundamentally different from their digital counterparts. Hence, to…

Information Theory · Computer Science 2017-08-08 Netanel Raviv , Moshe Schwartz , Eitan Yaakobi