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Proteins are macromolecules that mediate a significant fraction of the cellular processes that underlie life. An important task in bioengineering is designing proteins with specific 3D structures and chemical properties which enable…

Quantitative Methods · Quantitative Biology 2022-05-31 Namrata Anand , Tudor Achim

Neural networks based on soft and biological matter constitute an interesting potential alternative to traditional implementations based on electric circuits. DNA is a particularly promising system in this context due its natural ability to…

Biological Physics · Physics 2026-01-22 Michael te Vrugt

Cryptography is the science of using mathematics to encrypt and decrypt data. Cryptography enables you to store sensitive information or transmit it across insecure networks so that it cannot be read by anyone except the intended recipient.…

Cryptography and Security · Computer Science 2011-10-10 Penmetsa V. Krishna Raja , A. S. N. Chakravarthy , P. S. Avadhani

Ever since deoxyribonucleic acid (DNA) was considered as a next-generation data-storage medium, lots of research efforts have been made to correct errors occurred during the synthesis, storage, and sequencing processes using error…

Information Theory · Computer Science 2023-06-14 Jaeho Jeong , Hosung Park , Hee-Youl Kwak , Jong-Seon No , Hahyeon Jeon , Jeong Wook Lee , Jae-Won Kim

An information is a message which is received and understood. Information can be sent one person to another over a long range but the process of sending information must be done in a secure way especially in case of a private message.…

Cryptography and Security · Computer Science 2012-06-20 Yousuf Ibrahim Khan

The lack of uniqueness arising by oversampling of Fourier coefficients is shown to provide a way of transmitting hidden information. A basic encoding/decoding system, developed on the basis of such a possibility, is discussed. The system is…

General Mathematics · Mathematics 2007-05-23 Jody R. Miotke , Laura Rebollo-Neira

Biomolecular communication demands that interactions between parts of a molecular system act as scaffolds for message transmission. It also requires an evolving and organized system of signs - a communicative agency - for creating and…

Biomolecules · Quantitative Biology 2023-09-04 Gustavo Caetano-Anollés

Nucleic acids and proteins are not only biologically important polymers: They have recently been recognized as novel functional materials surpassing in many aspects the conventional ones. Although Herculean efforts have been undertaken to…

Soft Condensed Matter · Physics 2010-06-17 Waleed Shinwari , Jamal Deen , Evgeni Starikov , Gianaurelio Cuniberti

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

Ensembl's human non-coding and protein coding genes are used to automatically find DNA pattern motifs. The Backus-Naur form (BNF) grammar for regular expressions (RE) is used by genetic programming to ensure the generated strings are legal.…

Biomolecules · Quantitative Biology 2010-02-02 W. B. Langdon , Olivia Sanchez Graillet , A. P. Harrison

While RNA has recently been recognized as an interesting small-molecule drug target, many challenges remain to be addressed before we take full advantage of it. This emphasizes the necessity to improve our understanding of its structures…

Biomolecules · Quantitative Biology 2025-07-15 Rafael Josip Penić , Tin Vlašić , Roland G. Huber , Yue Wan , Mile Šikić

Expanding genetic codes from natural standard nucleotides to artificial non-standard nucleotides marks a significant advancement in synthetic biology, with profound implications for biotechnology and medicine. Decoding the biological…

Genomics · Quantitative Biology 2024-09-17 Hyunjin Shim

Evolution of genetic code is studied as the change in the choice of enzymes that are used to synthesize amino acids from the genetic information of nucleic acids. We propose the following theory: the differentiation of physiological states…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 H. Takagi , K. Kaneko , T. Yomo

The origin of life is one of the greatest mysteries. The mechanism for the synthesis of DNA is synonymous with the chemical origin of life, and theories have been developed along many lines of reasoning, but resolving all requirements…

Other Quantitative Biology · Quantitative Biology 2020-07-07 Charles D. Schaper

The genetic code maps the sixty-four nucleotide triplets (codons) to twenty amino-acids. While the biochemical details of this code were unraveled long ago, its origin is still obscure. We review information-theoretic approaches to the…

Genomics · Quantitative Biology 2010-07-23 Tsvi Tlusty

It is possible to interpret text as numbers (and vice versa) if one interpret letters and other characters as digits and assume that they have an inherent immutable ordering. This is demonstrated by the conventional digit set of the…

Cryptography and Security · Computer Science 2023-06-06 Armin Hoenen

DNA strands serve as a storage medium for $4$-ary data over the alphabet $\{A,T,G,C\}$. DNA data storage promises formidable information density, long-term durability, and ease of replicability. However, information in this intriguing…

Information Theory · Computer Science 2024-08-06 Canberk İrimağzı , Yusuf Uslan , Ahmed Hareedy

We describe a strategy for constructing codes for DNA-based information storage by serial composition of weighted finite-state transducers. The resulting state machines can integrate correction of substitution errors; synchronization by…

Information Theory · Computer Science 2016-11-18 Ian Holmes

A fundamental design rule that nature has developed for biological machines is the intimate correlation between motion and function. One class of biological machines is molecular motors in living cells, which directly convert chemical…

Biological Physics · Physics 2021-05-11 Na Liu

In this paper, we consider the problem of designing DNA sequences (codewords) for DNA storage systems and DNA computing that are unlikely to fold back onto themselves to form undesirable secondary structures. The paper addresses both the…

Discrete Mathematics · Computer Science 2016-11-17 Olgica Milenkovic , Navin Kashyap