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We call {\it monomer} a B-DNA base-pair and examine, analytically and numerically, electron or hole oscillations in monomer- and dimer-polymers, i.e., periodic sequences with repetition unit made of one or two monomers. We employ a…

Nucleic acids and proteins are not only biologically important polymers: They have recently been recognized as novel functional materials surpassing in many aspects the conventional ones. Although Herculean efforts have been undertaken to…

Soft Condensed Matter · Physics 2010-06-17 Waleed Shinwari , Jamal Deen , Evgeni Starikov , Gianaurelio Cuniberti

In this work we report the study of conformation dependent electronic transport properties of DNA double-helix within tight-binding framework including its helical symmetry. We have studied the changes in localization properties of DNA as…

Mesoscale and Nanoscale Physics · Physics 2022-06-20 Sourav Kundu , S. N. Karmakar

Literature data on the properties of DNA open states are reviewed and analyzed. These states are formed as a result of strong DNA fluctuations and have a great impact on a number of biochemical processes; among them is charge transfer in…

Biomolecules · Quantitative Biology 2020-02-04 A. S. Shigaev , O. A. Ponomarev , V. D. Lakhno

The characteristics of cation radical (hole) migration in heterogeneous DNA were investigated on the basis of Kubo formula, in which correlation functions were obtained from solutions of systems of Bogoliubov hierarchy. The cutting of…

Other Condensed Matter · Physics 2013-08-02 O. A. Ponomarev , A. S. Shigaev , A. I. Zhukov , V. D. Lakhno

The passage of DNA through a nanopore can be effectively decomposed into two distinct phases, docking and actual translocation. In experiments each phase is characterized by a distinct current signature which allows the discrimination of…

Electronic properties of DNA are believed to play a crucial role in many phenomena in living organisms, for example the location of DNA lesions by base excision repair (BER) glycosylases and the regulation of tumor-suppressor genes such as…

Other Quantitative Biology · Quantitative Biology 2012-02-21 Chi-Tin Shih , Stephen A. Wells , Ching-Ling Hsu , Yun-Yin Cheng , Rudolf A. Römer

The electrical conduction properties of G4-DNA are investigated using a hybrid approach, which combines electronic structure calculations, molecular dynamics (MD) simulations, and the formulation of an effective tight-binding model…

Various charge migration mechanisms in the DNA are studied within the framework of the Peyrard-Bishop-Holstein model which has been widely used to address charge dynamics in this macromolecule. To analyze these mechanisms we consider…

Biological Physics · Physics 2022-09-14 R. P. A. Lima , A. V. Malyshev

It is shown that in a Holstein molecular chain placed in a strong longitudinal electric field some new types of excitations can arise. This excitations can transfer a charge over large distance (more than 1000 nucleotide pairs) along the…

Mesoscale and Nanoscale Physics · Physics 2014-04-09 A. N. Korshunova , V. D. Lakhno

A genetic switch may be realised by a certain operator sector on the DNA strand from which either genetic code, to the left or to the right of this operator sector, can be transcribed and the corresponding information processed. This switch…

Statistical Mechanics · Physics 2013-01-24 Ralf Metzler

In eukaryotic genomes, nucleosomes function to compact DNA and to regulate access to it both by simple physical occlusion and by providing the substrate for numerous covalent epigenetic tags. While nucleosome positions in vitro are…

By means of the concept of factorial moment the charge transfer rates in DNA segments with fractal structures are investigated. An analytical form for the electron transfer rate is obtained.

Disordered Systems and Neural Networks · Physics 2007-05-23 Huijie Yang , Fangcui Zhao , Chunchun Liu , Yingli Zhao , Wenxiu Yang , Beilai Hu

The current - voltage dependence of the transverse tunneling current through the electron or hole traps in a DNA is investigated. The hopping of the charge between the sites of the trap and the charge-phonon coupling results in a staircase…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 V. Apalkov , T. Chakraborty

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

Quantum effects are mainly used for the determination of molecular shapes in molecular biology, but quantum information theory may be a more useful tool to understand the physics of life. Organic molecules and quantum circuits/protocols can…

Quantum Physics · Physics 2011-04-01 Onur Pusuluk , Cemsinan Deliduman

In this work we propose a model for DNA double helix within the tight-binding framework that incorporates the helicity of the molecules. We have studied localization properties of three DNAsequences,the periodic poly(dG)-poly(dC) and…

Mesoscale and Nanoscale Physics · Physics 2015-07-27 Sourav Kundu , S. N. Karmakar

Charge transport through a short DNA oligomer (Dickerson dodecamer) in presence of structural fluctuations is investigated using a hybrid computational methodology based on a combination of quantum mechanical electronic structure…

Soft Condensed Matter · Physics 2015-05-14 R. Gutierrez , R. Caetano , P. B. Woiczikowski , T. Kubar , M. Elstner , G. Cuniberti

We study the electronic transport through short DNA chains with various sequences of base pairs between voltage-biased leads. The strong coupling of the charge carriers to local vibrations of the base pairs leads to the formation of…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Benjamin B. Schmidt , Matthias H. Hettler , Gerd Schön

The free energy of looping DNA by proteins and protein complexes determines to what extent distal DNA sites can affect each other. We inferred its in vivo value through a combined computational-experimental approach for different lengths of…

Biomolecules · Quantitative Biology 2007-05-23 Leonor Saiz , J. Miguel Rubi , Jose M. G. Vilar