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We develop two mathematical lumped parameter models for blood pressure distribution in the Fontan blood flow circulation: an ODE based spatially homogeneous model and a PDE based spatially inhomogeneous model. We present numerical…

Analysis of PDEs · Mathematics 2018-06-08 J. P. Keener , M. Chugunova , R. M. Taranets , M. G. Doyle

- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

We consider a poromechanics model including frictionless contact mechanics. The resulting model consists of the Biot equations with contact boundary conditions leading to a variational inequality modelling mechanical deformations coupled to…

Numerical Analysis · Mathematics 2024-07-19 Tameem Almani , Kundan Kumar

Parabolic partial differential equations (PDEs) appear in many disciplines to model the evolution of various mathematical objects, such as probability flows, value functions in control theory, and derivative prices in finance. It is often…

Machine Learning · Computer Science 2024-07-18 Xingzi Xu , Ali Hasan , Jie Ding , Vahid Tarokh

Spatial reaction-diffusion models have been employed to describe many emergent phenomena in biological systems. The modelling technique most commonly adopted in the literature implements systems of partial differential equations (PDEs),…

Quantitative Methods · Quantitative Biology 2015-10-05 Christian A. Yates , Mark B. Flegg

Statistical systems with time-periodic spatially non-uniform forces are of immense importance in several areas of physics. In this paper, we provide an analytical expression of the time-periodic probability distribution function of…

Plasma Physics · Physics 2015-10-15 Kushal Shah , Balaji Srinivasan

In this work, we consider the coupled systems of linear unsteady partial differential equations, which arise in the modeling of poroelasticity processes. Stability estimates of weighted difference schemes for the coupled system of equations…

Numerical Analysis · Computer Science 2013-11-18 A. E. Kolesov , P. N. Vabishchevich , M. V. Vasilyeva

Many physical systems are governed by ordinary or partial differential equations (see, for example, Chapter ''Differential equations'', ''System of Differential Equations''). Typically the solution of such systems are functions of time or…

Numerical Analysis · Mathematics 2023-09-06 Clarissa Astuto , Giovanni Russo

The macroscopic behavior of the solution of a coupled system of partial differential equations arising in the modeling of reaction-diffusion processes in periodic porous media is analyzed. Our mathematical model can be used for studying…

Analysis of PDEs · Mathematics 2019-06-19 G. Cardone , C. Perugia , C. Timofte

This paper deals with the existence of solutions for an elliptic system of partial differential equations. The solution method is based on the sub- and super-solutions approach. An application to a stochastic control problem is presented.…

Analysis of PDEs · Mathematics 2020-01-01 Dragos-Patru Covei , Traian A. Pirvu

We propose and analyse the properties of a new class of models for the electromechanics of cardiac tissue. The set of governing equations consists of nonlinear elasticity using a viscoelastic and orthotropic exponential constitutive law…

Numerical Analysis · Mathematics 2022-04-08 Adrienne Propp , Alessio Gizzi , Francesc Levrero-Florencio , Ricardo Ruiz-Baier

Blood system functions are very diverse and important for most processes in human organism. One of its primary functions is matter transport among different parts of the organism including tissue supplying with oxygen, carbon dioxide…

Biological Physics · Physics 2007-12-31 A. S. Kholodov , S. S. Simakov , Y. A. Kholodov , A. A. Nadolsky , A. N. Shushlebin

A new method is proposed to numerically extract the diffusivity of a (typically nonlinear) diffusion equation from underlying stochastic particle systems. The proposed strategy requires the system to be in local equilibrium and have…

Statistical Mechanics · Physics 2018-05-09 Peter Embacher , Nicolas Dirr , Johannes Zimmer , Celia Reina

We investigate systems of degenerate parabolic equations idealizing reactive solute transport in porous media. Taking advantage of the inherent structure of the system that allows to deduce a scalar Generalized Porous Medium Equation for…

Analysis of PDEs · Mathematics 2014-12-19 Tuomo Kuusi , Léonard Monsaingeon , Juha Videman

The bidomain system of degenerate reaction-diffusion equations is a well-established spatial model of electrical activity in cardiac tissue, with "reaction" linked to the cellular action potential and "diffusion" representing current flow…

Analysis of PDEs · Mathematics 2018-03-26 Mostafa Bendahmane , Kenneth H. Karlsen

A discrete time model that is capable of replicating the basic features of cardiac cell action potentials is suggested. The paper shows how the map-based approaches can be used to design highly efficient computational models (algorithms)…

Cell Behavior · Quantitative Biology 2007-08-10 Nikolai F. Rulkov

The arterial system dynamically loads the heart through changes in arterial compliance. The pressure-volume relation of arteries is known to be nonlinear, but arterial compliance is often modeled as a constant value, due to ease of…

Quantitative Methods · Quantitative Biology 2014-03-26 Timothy S. Phan , John K-J. Li

This overview is devoted to splitting methods, a class of numerical integrators intended for differential equations that can be subdivided into different problems easier to solve than the original system. Closely connected with this class…

Numerical Analysis · Mathematics 2024-05-08 Sergio Blanes , Fernando Casas , Ander Murua

Polynomials are common algebraic structures, which are often used to approximate functions including probability distributions. This paper proposes to directly define polynomial distributions in order to describe stochastic properties of…

Information Theory · Computer Science 2022-12-12 Yue Yu , Pavel Loskot
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