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Related papers: Molecular Motors Interacting with Their Own Tracks

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Biological molecular motors are high-performance nanomachines that convert chemical energy into mechanical motion via chemomechanical coupling. Their reaction cycles typically comprise a series of intermediate chemical states between the…

Biological Physics · Physics 2025-05-26 Akihiro Fukuda , Yohei Nakayama , Shoichi Toyabe

Manipulating and coupling molecule gears is the first step towards realizing molecular-scale mechanical machines. Here, we theoretically investigate the behavior of such gears using molecular dynamics simulations. Within a nearly rigid-body…

Soft Condensed Matter · Physics 2020-03-12 H. -H. Lin , A. Croy , R. Gutierrez , C. Joachim , G. Cuniberti

The collective behavior of molecular motor proteins have been investigated in the literature using models to describe the long-time dynamics of a unidimensional continuum motor distribution. Here, we consider the phenomena related to the…

Subcellular Processes · Quantitative Biology 2008-03-20 Daniel Gomes Lichtenthaler , Carla Goldman

Microscopic dynamical aspects of the propulsion of nanomotors by self-phoretic mechanisms are considered. Propulsion by self-diffusiophoresis relies on the mechanochemical coupling between the fluid velocity field and the concentration…

Statistical Mechanics · Physics 2018-01-04 Pierre Gaspard , Raymond Kapral

We investigate the dependence of the displacements of a molecular motor embedded inside a glassy material on its folding characteristic time. We observe two different time regimes. For slow foldings (regime I) the diffusion evolves very…

Motor proteins are active enzyme molecules that play a crucial role in many biological processes. They transform the chemical energy into the mechanical work and move unidirectionally along rigid cytoskeleton filaments. Single-molecule…

Soft Condensed Matter · Physics 2009-11-13 Rahul Kumar Das , Anatoly B. Kolomeisky

A model of an autonomous isothermal Brownian motor with an internal propulsion mechanism is considered. The motor is a Brownian particle which is semi-transparent for molecules of surrounding ideal gas. Molecular passage through the…

Statistical Mechanics · Physics 2015-06-15 A. V. Plyukhin

In recent years, several artificial molecular motors driven and controlled by electric currents have been proposed. Similar to Brownian machines, these systems work by turning random inelastic tunneling events into a directional rotation of…

Mesoscale and Nanoscale Physics · Physics 2022-10-31 Federico D. Ribetto , Sebastián E. Deghi , Hernán L. Calvo , Raúl A. Bustos-Marún

Molecular motors do not work in isolation {\it in-vivo}. We highlight some of the coordinations, cooperations and competitions that determine the collective properties of molecular motors in eukaryotic cells. In the context of traffic-like…

Biological Physics · Physics 2009-04-16 Debashish Chowdhury

General discrete one-dimensional stochastic models to describe the transport of single molecules along coupled parallel lattices with period $N$ are developed. Theoretical analysis that allows to calculate explicitly the steady-state…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

Janus motors with chemically active and inactive hemispheres can operate only under nonequilibrium conditions where detailed balance is broken by fluxes of chemical species that establish a nonequilibrium state. A microscopic model for…

Soft Condensed Matter · Physics 2018-08-01 Mu-Jie Huang , Jeremy Schofield , Pierre Gaspard , Raymond Kapral

We introduce a model for translational molecular motors to demonstrate that a multivalent catalytic walker with flexible, uncoordinated legs can transform the free energy of surface-bound substrate sites into mechanical work and undergo…

Biological Physics · Physics 2014-11-18 Mark J. Olah , Darko Stefanovic

Many cellular processes rely on the cell's ability to transport material to and from the nucleus. Networks consisting of many microtubules and actin filaments are key to this transport. Recently, the inhibition of intracellular transport…

Subcellular Processes · Quantitative Biology 2020-05-06 Shawn D. Ryan , Zachary McCarthy , Mykhailo Potomkin

The breakup dynamics of viscous liquid bridges on solid surfaces is studied experimentally. It is found that the dynamics bears similarities to the breakup of free liquid bridges in the viscous regime. Nevertheless, the dynamics is…

Fluid Dynamics · Physics 2024-08-06 Salar Farokhi , Peyman Rostami , Günter K. Auernhammer , Steffen Hardt

Biomolecular machines transduce between different forms of energy. These machines make directed progress and increase their speed by consuming free energy, typically in the form of nonequilibrium chemical concentrations. Machine dynamics…

Statistical Mechanics · Physics 2018-10-05 Aidan I Brown , David A Sivak

Motor-driven cytoskeletal remodeling in cellular systems can often be accompanied by a diffusive-like effect at local scales, but distinguishing the contributions of the ordering process, such as active contraction of a network, from this…

Biological Physics · Physics 2024-08-22 Soichi Hirokawa , Heun Jin Lee , Rachel A Banks , Ana I Duarte , Bibi Najma , Matt Thomson , Rob Phillips

We consider an interacting particle system on the one dimensional lattice $\bf Z$ modeling combustion. The process depends on two integer parameters $2\le a<M<\infty$. Particles move independently as continuous time simple symmetric random…

Probability · Mathematics 2016-09-07 Francis Comets , Jeremy Quastel , Alejandro F. Ramirez

We consider an explicit model of a semiflexible filament moving in two dimensions on a gliding assay of motor proteins, which attach to and detach from filament segments stochastically, with a detachment rate that depends on the local load…

Soft Condensed Matter · Physics 2019-05-23 Nisha Gupta , Abhishek Chaudhuri , Debasish Chaudhuri

Molecular dynamics simulations of folding in an off-lattice protein model reveal a nucleation scenario, in which a few well-defined contacts are formed with high probability in the transition state ensemble of conformations. Their…

Statistical Mechanics · Physics 2009-09-25 Nikolay V. Dokholyan , Sergey V. Buldyrev , H. Eugene Stanley , Eugene I. Shakhnovich

Individual processive molecular motors, of which conventional kinesin is the most studied quantitatively, move along polar molecular tracks and, by exerting a force ${\bm F} = (F_x,F_y,F_z)$ on a tether, drag cellular cargoes, {\em in…

Statistical Mechanics · Physics 2015-06-25 Young C. Kim , Michael E. Fisher
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