Related papers: Modelling background intensity in Affymetrix Genec…
Gravitational wave detections offer insights into the astrophysical populations of black holes in the universe and their formation processes. Detections of binaries consisting of black holes lying outside the bulk distribution of the…
We consider the problem of detecting and estimating the strength of association between a trait of interest and alleles or haplotypes in a small genomic region (e.g. a gene or a gene complex), when no direct information on that region is…
Intensity mapping is a promising technique for surveying the large scale structure of our Universe from $z=0$ to $z \sim 150$, using the brightness temperature field of spectral lines to directly observe previously unexplored portions of…
Ground-based observations at thermal infrared wavelengths suffer from large background radiation due to the sky, telescope and warm surfaces in the instrument. This significantly limits the sensitivity of ground-based observations at…
We present imaging and force spectroscopy measurements of DNA molecules adsorbed on functionalized mica. By means of Non-Contact mode AFM (NC-AFM) in Ultra High Vacuum (UHV), the frequency shift (\Delta f) versus separation (z) curves were…
The ability of oligonucleotide microarrays to measure gene expression has been hindered by an imperfect understanding of the relationship between input RNA concentrations and output signals. We argue that this relationship can be understood…
Many experiments that aim at the direct detection of Dark Matter are able to distinguish a dominant background from the expected feeble signals, based on some measured discrimination parameter. We develop a statistical model for such…
While GNN-based detection methods excel at identifying overt outliers, they often struggle with boundary anomalies -- subtly camouflaged nodes that are difficult to distinguish from normal instances. This limitation highlights a fundamental…
We present a novel graphical framework for modeling non-negative sequential data with hierarchical structure. Our model corresponds to a network of coupled non-negative matrix factorization (NMF) modules, which we refer to as a positive…
Motivation: Array Comparative Genomic Hybridization (aCGH) is used to scan the entire genome for variations in DNA copy number. A central task in the analysis of aCGH data is the segmentation into groups of probes sharing the same DNA copy…
Over the past few years, there has been a considerable spread of microarray technology in many biological patterns, particularly in those pertaining to cancer diseases like leukemia, prostate, colon cancer, etc. The primary bottleneck that…
Alpha emission from actinide impurities in Al is a source of background counting rate in Multi-Grid type detectors of thermal neutrons. The alpha emission rates from samples of radio-purity Al and \mathrm{Al/B_{4}C} composite, used in grid…
We consider the problem of assembling a sequence based on a collection of its substrings observed through a noisy channel. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on…
Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) and their biological significance is often difficult. Currently, the…
Analysis of pulsar timing data have provided evidence for a stochastic gravitational wave background in the nHz frequency band. The most plausible source of such a background is the superposition of signals from millions of supermassive…
Existing single-image denoising algorithms often struggle to restore details when dealing with complex noisy images. The introduction of near-infrared (NIR) images offers new possibilities for RGB image denoising. However, due to the…
Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…
Accurate background estimation is essential for spectral and temporal analysis in astrophysics. In this work, we construct the in-orbit background model for the High-Energy Telescope (HE) of the Hard X-ray Modulation Telescope (dubbed as…
Exquisite sensitivities are a prominent advantage of quantum sensors. Ramsey sequences allow precise measurement of direct current fields, while Hahn-echo-like sequences measure alternating current fields. However, the latter are restrained…
MicroRNAs are endogenous non-coding RNAs which negatively regulate the expression of protein-coding genes in plants and animals. They are known to play an important role in several biological processes and, together with transcription…