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Related papers: Morphogenesis of growing soft tissues

200 papers

When stretched in one direction, most solids shrink in the transverse directions. In soft silicone gels, however, we observe that small-scale topographical features grow upon stretching. A quantitative analysis of the topography shows that…

Many tissues take the form of thin sheets, being only a single cell thick, but millions of cells wide. These tissue sheets can bend and buckle in the third dimension. In this work, we investigated the growth and shrinkage of suspended and…

Biological Physics · Physics 2024-11-01 Hiroshi Noguchi , Jens Elgeti

The phenomenological model for cell shape deformation and cell migration (Chen et.al. 2018; Vermolen and Gefen 2012) is extended with the incorporation of cell traction forces and the evolution of cell equilibrium shapes as a result of cell…

Cell Behavior · Quantitative Biology 2021-04-27 Qiyao Peng , Fred Vermolen , Daphne Weihs

A model for morphoelastic growth, that is, growth influenced by elastic stress, driven by the absorption of nutrients is considered. The model features a multiplicative decomposition of the deformation gradient into an elastic contribution…

Analysis of PDEs · Mathematics 2026-05-05 Helmut Abels , Julian Blawid , Georg Dolzmann

Epithelial tissues play a fundamental role in various morphogenetic events during development and early embryogenesis. Although epithelial monolayers are often modeled as two-dimensional (2D) elastic surfaces, they distinguish themselves…

Soft Condensed Matter · Physics 2020-06-15 Benjamin Loewe , Francesco Serafin , Suraj Shankar , Mark J. Bowick , M. Cristina Marchetti

Growth occurs in a wide range of systems ranging from biological tissue to additive manufacturing. This work considers surface growth, in which mass is added to the boundary of a continuum body from the ambient medium or from within the…

Analysis of PDEs · Mathematics 2021-05-27 Kiana Naghibzadeh , Noel Walkington , Kaushik Dayal

Incompressibility, nonlinear deformation under stress and viscoelasticity are the fingerprint of soft tissue mechanical behavior. In order to model soft tissues appropriately, we must pursue to complete these requirements. In this work we…

Other Computer Science · Computer Science 2016-08-16 J. S. Espinoza Ortiz , Gilson A. Giraldi , E. A. de Souza Neto , Raul A. Feijóo

Thin elastic sheets appear in systems ranging from graphene to biological membranes, where phenomena such as wrinkling, folding, and thermal fluctuations originate from geometric nonlinearities. These effects are treated within weakly…

Soft Condensed Matter · Physics 2025-12-04 Yael Cohen , Animesh Pandey , Yafei Zhang , Cy Maor , Michael Moshe

We discuss shape profiles emerging in inhomogeneous growth of squeezed tissues. Two approaches are used simultaneously: i) conformal embedding of two-dimensional domain with hyperbolic metrics into the plane, and ii) a pure energetic…

Soft Condensed Matter · Physics 2015-11-25 Sergei Nechaev , Kirill Polovnikov

Natural slender structures, such as plant leaves, petals, and tendrils, often exhibit complex three-dimensional (3D) morphologies-including twisting, helical coiling, and saddle-bending-driven by differential growth. The resulting internal…

Soft Condensed Matter · Physics 2025-06-24 Hao Liu , Mingwu Li , Dabiao Liu

How do cells tune emergent properties at the scale of tissues? One class of such emergent behaviors are rigidity transitions, in which a tissue changes from a solid-like to a fluid-like state or vice versa. Here, we introduce a new way for…

Soft Condensed Matter · Physics 2025-06-04 Sadjad Arzash , Indrajit Tah , Andrea J. Liu , M. Lisa Manning

Tissue growth underpins a wide array of biological and developmental processes, and numerical modeling of growing systems has been shown to be a useful tool for understanding these processes. However, the phenomena that can be captured are…

Soft Condensed Matter · Physics 2023-11-08 Andrew Killeen , Benjamin Partridge , Thibault Bertrand , Chiu Fan Lee

Extreme deformation of soft matter is central to our understanding of the effects of shock, fracture, and phase change in a variety of systems. Yet, despite, the increasing interest in this area, far-from-equilibrium behaviours of soft…

Soft Condensed Matter · Physics 2020-07-07 Axel Huerre , Marco De Corato , Valeria Garbin

A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…

Tissues and Organs · Quantitative Biology 2017-09-06 Shuji Ishihara , Philippe Marcq , Kaoru Sugimura

We explain the linear growth of smooth solid helium facets by the presence of lattice point defects. To implement this task, the framework of very general two-velocity elasticity theory equations is developed. Boundary conditions for these…

Statistical Mechanics · Physics 2007-05-23 A. F. Andreev , L. A. Melnikovsky

We consider some basic principles of fluid-induced lubrication at soft interfaces. In particular, we show how the presence of a soft substrate leads to an increase in the physical separation between surfaces sliding past each other. By…

Soft Condensed Matter · Physics 2009-11-10 J. M. Skotheim , L. Mahadevan

We study equilibrium shapes and shape transformations of a confined semiflexible chain inside a soft lipid tubule using simulations and continuum theories. The deformed tubular shapes and chain conformations depend on the relative magnitude…

Soft Condensed Matter · Physics 2020-06-11 Subhadip Biswas , Buddhapriya Chakrabarti

The growth of several biological tissues is known to be controlled in part by local geometrical features, such as the curvature of the tissue interface. This control leads to changes in tissue shape that in turn can affect the tissue's…

Tissues and Organs · Quantitative Biology 2016-12-01 Almie Alias , Pascal R Buenzli

Morphoelasticity represents a foundational theory for tracing back growth, remodelling, and morphogenesis, yet crucial challenges persist. A unified growth law -- independent of a priori assumptions about constitutive relations or specified…

Soft Condensed Matter · Physics 2025-07-29 Angelo Rosario Carotenuto , Stefania Palumbo , Arsenio Cutolo , Massimiliano Fraldi

We study how the encasement of a growing elastic bulk within a possibly differently growing elastic coat may induce mechanical instabilities in the equilibrium shape of the combined body. The inhomogeneities induced in an incompressible…

Soft Condensed Matter · Physics 2023-07-19 Paolo Biscari , Pier Luigi Susini , Giovanni Zanzotto