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Related papers: Morphogenesis of growing soft tissues

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We address the folding induced by differential growth in soft layered solids via an elementary model that consists of a soft growing neo-Hookean elastic layer adhered to a deep elastic substrate. As the layer/substrate modulus ratio is…

Soft Condensed Matter · Physics 2015-09-30 Tuomas Tallinen , John S. Biggins

We investigate morphologies of proliferating cellular tissue using a newly developed numerical simulation model for mechanical cell division. The model reproduces structures of simple multi-cellular organisms via simple rules for selective…

Soft Condensed Matter · Physics 2018-11-20 Pranav Madhikar , Jan Åström , Björn Baumeier , Mikko Karttunen

We present some existence results for three-dimensional quasistatic morphoelasticity. The state of the growing body is described by its deformation and the underlying growth tensor and is ruled by the interplay of hyperelastic energy…

Analysis of PDEs · Mathematics 2021-11-23 Elisa Davoli , Katerina Nik , Ulisse Stefanelli

Morphoelastic rods are thin bodies which can grow and can change their intrinsic curvature and torsion. We deduce a system of equations ruling accretion and remodeling in a morphoelastic rod by combining balance laws involving non-standard…

Classical Physics · Physics 2014-10-24 Alessandro Tiero , Giuseppe Tomassetti

Models of tissue growth are now well established, in particular in relation to their applications to cancer. They describe the dynamics of cells subject to motion resulting from a pressure gradient generated by the death and birth of cells,…

Analysis of PDEs · Mathematics 2018-09-07 Piotr Gwiazda , Benoît Perthame , Agnieszka Świerczewska-Gwiazda

Various models of tumor growth are available in the litterature. A first class describes the evolution of the cell number density when considered as a continuous visco-elastic material with growth. A second class, describes the tumor as a…

Analysis of PDEs · Mathematics 2016-02-17 Benoit Perthame , Nicolas Vauchelet

Surface growth is a crucial component of many natural and artificial processes from cell proliferation to additive manufacturing. In elastic systems surface growth is usually accompanied by the development of geometrical incompatibility…

Soft Condensed Matter · Physics 2019-05-08 Lev Truskinovsky , Giuseppe Zurlo

The remarkable range of biological forms in and around us, such as the undulating shape of a leaf or flower in the garden, the coils in our gut, or the folds in our brain, raise a number of questions at the interface of biology, physics and…

General Mathematics · Mathematics 2021-05-13 Marta Lewicka , L. Mahadevan

The growth dynamics of rigid biopolymers, consisting of $N$ parallel protofilaments, is investigated theoretically using simple approximate models. In our approach, the structure of a polymer's growing end and lateral interactions between…

Statistical Mechanics · Physics 2009-11-10 Evgeny B. Stukalin , Anatoly B. Kolomeisky

During the development of an organism, cells must coordinate and organize to generate the correct shape, structure, and spatial patterns of tissues and organs, a process known as morphogenesis. The morphogenesis of embryonic tissues is…

Tissues and Organs · Quantitative Biology 2026-04-28 Adrian Aguirre-Tamaral , Elisa Floris , Bernat Corominas-Murtra

In this study, we explore a mathematical model for tissue growth focusing on the interplay between multiple cell subpopulations with distinct phenotypic characteristics. The model addresses the dynamics of tissue growth influenced by…

Analysis of PDEs · Mathematics 2024-09-05 Tomasz Dębiec , Mainak Mandal , Markus Schmidtchen

Soft elastic sheets resting on rigid surfaces develop wrinkles, rucks, and folds due to the combined influence of elasticity, gravity, and contact interactions. Despite their ubiquity, the principles governing their morphology and…

Soft Condensed Matter · Physics 2026-05-18 Keisuke Yoshida , Hirofumi Wada

Plant morphogenesis relies on dynamic growth deformations at the cell and tissue scales driven by osmotic fluxes. A mechanistic understanding of this phenomenon demands a physical framework that integrates cell imbibition, tissue mechanics,…

Biological Physics · Physics 2025-12-08 Hadrien Oliveri , Christophe Godin , Ibrahim Cheddadi

Localized deformation patterns are a common motif in morphogenesis and are increasingly finding widespread applications in materials science, for instance as memory devices. Here we describe the emergence of spatially localized deformations…

Soft Condensed Matter · Physics 2019-06-12 Thomas C. T. Michaels , Remy Kusters , Alexander J. Dear , Cornelis Storm , James C. Weaver , L. Mahadevan

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

A central question in developmental biology is how size and position are determined. The genetic code carries instructions on how to control these properties in order to regulate the pattern and morphology of structures in the developing…

Cell Behavior · Quantitative Biology 2016-12-05 Krishna Garikipati

In [B] Bowen defined the growth rate of an endomorphism of a finitely generated group and related it to the entropy of a map $f:M \mapsto M$ on a compact manifold. In this note we study the purely group theoretic aspects of the growth rate…

Group Theory · Mathematics 2011-03-30 Kenneth Falconer , Benjamin Fine , Delaram Kahrobaei

Mollusk shells are an ideal model system for understanding the morpho-elastic basis of morphological evolution of invertebrates' exoskeletons. During the formation of the shell, the mantle tissue secretes proteins and minerals that calcify…

Quantitative Methods · Quantitative Biology 2019-08-12 Shiva Rudraraju , Derek E. Moulton , Régis Chirat , Alain Goriely , Krishna Garikipati

We propose a two-scale model to resolve essential features of developmental tissue deformations. The model couples individual cellular behavior to the mechanics at tissue scale. This is realized by a multiphase-field model addressing the…

Soft Condensed Matter · Physics 2025-06-25 Lea Happel , Axel Voigt

Morphogenesis, the process by which an adult organism emerges from a single cell, has fascinated humans for a long time. Modelling this process can provide novel insights into development and the principles that orchestrate the…

Tissues and Organs · Quantitative Biology 2018-06-13 M. D. Peters , L. D. Wittwer , A. Stopka , D. Barac , C. Lang , D. Iber