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We performed integrated modelling of the chemical pathways of formation for boron nitride nanotube (BNNT) precursors during high-temperature synthesis in a B/N2 mixture. Modelling includes quantum chemistry, quantum-classical molecular…

Purpose: To improve target coverage and reduce the dose in the surrounding organs-at-risks (OARs), we developed an image-guided treatment method based on a precomputed library of treatment plans controlled and delivered in real-time.…

Medical Physics · Physics 2022-11-02 Valentin Hamaide , Kevin Souris , Damien Dasnoy , Francois Glineur , Benoit Macq

Thermal neutron detectors are crucial to a wide range of applications, including nuclear safety and security, cancer treatment, space research, non-destructive testing, and more. However, neutrons are notoriously difficult to capture due to…

Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…

Medical Physics · Physics 2024-11-14 R. M. Winter , O. Engelsen , O. J. Bratting , N. Brekke , J. Sæterstøl , O. Sæther , K. R. Redalen

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

A multilayer surface detector for ultracold neutrons (UCNs) is described. The top $^{10}$B layer is exposed to the vacuum chamber and directly captures UCNs. The ZnS:Ag layer beneath the $^{10}$B layer is a few microns thick, which is…

Neutron scattering techniques offer a unique combination of structural and the dynamic information of atomic and molecular systems over a wide range of distances and times. The increasing complexity in science investigations driven by…

Instrumentation and Detectors · Physics 2019-05-30 Giacomo Mauri

The long-term efficacy of targeted therapeutics for cancer treatment can be significantly limited by the type of therapy and development of drug resistance, inter alia. Experimental studies indicate that the factors enhancing acquisition of…

Tissues and Organs · Quantitative Biology 2021-02-16 Joseph Malinzi , Kevin Bosire Basita , Sara Padidar , Henry A. Adeola

Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. Real-time range…

Medical Physics · Physics 2018-10-17 Kristian Smeland Ytre-Hauge , Kyrre Skjerdal , John Mattingly , Ilker Meric

The quantification of isotopes content in materials is extremely important in many research and industrial fields. Accurate determination of boron concentration is very critical in semiconductor, superconductor and steel industry, in…

Nuclear Experiment · Physics 2019-10-03 A. Caciolli , R. Depalo , V. Rigato

The development of the $\beta^-$ based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the…

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

A new boron-coated CCD camera is described for direct detection of ultracold neutrons (UCN) through the capture reactions $^{10}$B (n,$\alpha$0$\gamma$)$^7$Li (6%) and $^{10}$B(n,$\alpha$1$\gamma$)$^7$Li (94%). The experiments, which extend…

Purpose: Organ-at-risk (OAR) delineation is a key step for cone-beam CT (CBCT) based adaptive radiotherapy planning that can be a time-consuming, labor-intensive, and subject-to-variability process. We aim to develop a fully automated…

Poor tissue visualization and quantitative accuracy in CBCT is a major barrier in expanding the role of CBCT imaging from target localization to quantitative treatment monitoring and plan adaptations in radiation therapy sessions. To…

Medical Physics · Physics 2023-08-21 Farhang Bayat , Dan Ruan , Moyed Miften , Cem Altunbas

The neutron sensitivity of the C$_6$D$_6$ detector setup used at n_TOF for capture measurements has been studied by means of detailed GEANT4 simulations. A realistic software replica of the entire n_TOF experimental hall, including the…

Instrumentation and Detectors · Physics 2014-06-27 TOF collaboration , P. Žugec , N. Colonna , D. Bosnar , S. Altstadt , J. Andrzejewski , L. Audouin , M. Barbagallo , V. Bécares , F. Bečvář , F. Belloni , E. Berthoumieux , J. Billowes , V. Boccone , M. Brugger , M. Calviani , F. Calviño , D. Cano-Ott , C. Carrapiço , F. Cerutti , E. Chiaveri , M. Chin , G. Cortés , M. A. Cortés-Giraldo , M. Diakaki , C. Domingo-Pardo , R. Dressler , I. Duran , N. Dzysiuk , C. Eleftheriadis , A. Ferrari , K. Fraval , S. Ganesan , A. R. García , G. Giubrone , M. B. Gómez-Hornillos , I. F. Gonçalves , E. González-Romero , E. Griesmayer , C. Guerrero , F. Gunsing , P. Gurusamy , S. Heinitz , D. G. Jenkins , E. Jericha , Y. Kadi , F. Käppeler , D. Karadimos , N. Kivel , P. Koehler , M. Kokkoris , M. Krtička , J. Kroll , C. Langer , C. Lederer , H. Leeb , L. S. Leong , S. Lo Meo , R. Losito , A. Manousos , J. Marganiec , T. Martìnez , C. Massimi , P. F. Mastinu , M. Mastromarco , M. Meaze , E. Mendoza , A. Mengoni , P. M. Milazzo , F. Mingrone , M. Mirea , W. Mondalaers , C. Paradela , A. Pavlik , J. Perkowski , A. Plompen , J. Praena , J. M. Quesada , T. Rauscher , R. Reifarth , A. Riego , F. Roman , C. Rubbia , R. Sarmento , A. Saxena , P. Schillebeeckx , S. Schmidt , D. Schumann , G. Tagliente , J. L. Tain , D. Tarrío , L. Tassan-Got , A. Tsinganis , S. Valenta , G. Vannini , V. Variale , P. Vaz , A. Ventura , R. Versaci , M. J. Vermeulen , V. Vlachoudis , R. Vlastou , A. Wallner , T. Ware , M. Weigand , C. Weiß , T. Wright

The linear optical absorption spectra of three isomers of planar boron cluster B$_{13}$ are calculated using time-dependent spin-polarized density functional approach. The geometries of these cluster are optimized at the B3LYP/6-311+G*…

Atomic and Molecular Clusters · Physics 2013-02-12 Ravindra Shinde , Meenakshi Tayade

We report a model to predict patient's radiological response to curative radiation therapy (RT) for non-small-cell lung cancer (NSCLC). Cone-Beam Computed Tomography images acquired weekly during the six-week course of RT were contoured…

The reaction rates of neutron capture reactions on light nuclei are important for reliably simulating nucleosynthesis in a variety of stellar scenarios. Neutron capture reaction rates on neutron-rich C-, N-, and O-isotopes are calculated in…

Nuclear Theory · Physics 2008-11-26 H. Herndl , R. Hofinger , J. Jank , H. Oberhummer , J. Goerres , M. Wiescher , F. -K. Thielemann , B. A. Brown

We describe a novel experimental technique for neutron imaging with scattered neutrons. These scattered neutrons are of interest for condensed matter physics, because they permit to reveal the local distribution of incoherent and coherent…

Nuclear Experiment · Physics 2007-05-23 H. Ballhausen , H. Abele , R. Gaehler , M. Trapp , A. Van Overberghe