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The goal of this research project is to give quantitative information useful for the design of a g-ray detector to investigate neutron capture (n, g) reactions on radioactive nuclei at the Manuel Lujan Jr. Neutron Scattering Center (MLNSC)…
Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…
Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…
The continued interest to the study of the radiative neutron capture on atomic nuclei is caused, on the one hand, by the important role of this process in the analysis of many fundamental properties of nuclei and nuclear reactions, and, on…
Cone beam computed tomography (CBCT)-guided puncture has become an established approach for diagnosing and treating early- to mid-stage thoracic tumours, yet the associated radiation exposure substantially elevates the risk of secondary…
Multilayer position-sensitive 10B-RPC thermal neutron detectors offer an attractive combination of sub-millimeter spatial resolution and high (>50%) detection efficiency. Here we describe a new position reconstruction method based on a…
Neutron detection provides an effective method to detect, locate, and characterize sources of interest to nuclear security applications. Current neutron imaging systems based on double-scatter kinematic reconstruction provide good signal…
We present a nitrogen-targeting-Proton-Carbon-Alpha-Therapy method, abbreviated as Proton-CAT, which partially converts protons into carbon-12 and $\alpha$ particles through nuclear reactions between protons and nitrogen-15. Monte Carlo…
Purpose: Photon-counting computed tomography (PCCT) shows promise for medical imaging in regards to material separation and imaging of multiple contrast agents. However, many PCCT setups are under development and are not optimized for…
CT image-guided thermal ablation is widely used for lung cancer treatment; however, follow-up data indicate that physicians' subjective assessments of intraoperative images often overestimate the ablation effect, potentially leading to…
In this study we evaluated the task-based image quality of a low contrast clinical task for the abdomen protocol (e.g., pancreatic tumour) of three different CT vendors, exploiting three model-based iterative reconstruction (MBIR) levels.…
Tumor is heterogeneous - a tumor sample usually consists of a set of subclones with distinct transcriptional profiles and potentially different degrees of aggressiveness and responses to drugs. Understanding tumor heterogeneity is therefore…
Photon from neutron-proton bremsstrahlung in p+Pb reactions is examined as a potential probe of the neutron-skin thickness in different centralities and at different proton incident energies. It is shown that the best choice of reaction…
We report the first measurement of the $^{10}{\rm B}(\alpha,n)^{13}{\rm N}$ reaction in a polar-direct-drive exploding pusher (PDXP) at the National Ignition Facility (NIF). This work is motivated by the need to develop alternative mix…
Radiation therapy is a critical component of cancer treatment. However, the delivery of radiation poses inherent challenges, particularly in minimizing radiation exposure to healthy organs surrounding the tumor site. One significant…
Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combining the advantages of target coverage conformity and critical…
Although cone-beam CT (CBCT) has been used to guide irradiation for pre-clinical radiotherapy(RT) research, it is limited to localize soft tissue target especially in a low imaging contrast environment. Knowledge of target shape is a…
Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…
We study energy deposition by light nuclei in tissue-like media taking into account nuclear fragmentation reactions, in particular, production of secondary neutrons. The calculations are carried out within a Monte Carlo model for Heavy-Ion…
Within the framework of the modified potential cluster model with the forbidden states and the classification of states according to Young tableaux the possibility of describing the available experimental data for the total reaction cross…