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We propose a modelling framework to analyse the stochastic behaviour of heterogeneous, multi-scale cellular populations. We illustrate our methodology with a particular example in which we study a population with an oxygen-regulated…

Biological Physics · Physics 2017-09-01 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

Markov Population Models are a widespread formalism used to model the dynamics of complex systems, with applications in Systems Biology and many other fields. The associated Markov stochastic process in continuous time is often analyzed by…

Machine Learning · Computer Science 2021-06-25 Francesca Cairoli , Ginevra Carbone , Luca Bortolussi

Let $(X_t)_{t \geq 0}$ be a continuous time Markov process on some metric space $M,$ leaving invariant a closed subset $M_0 \subset M,$ called the {\em extinction set}. We give general conditions ensuring either "Stochastic persistence"…

Probability · Mathematics 2023-10-26 Michel Benaim

The diffusive epidemic process is a paradigmatic example of an absorbing state phase transition in which healthy and infected individuals spread with different diffusion constants. Using stochastic activity spreading simulations in…

Statistical Mechanics · Physics 2022-03-02 Borislav Polovnikov , Patrick Wilke , Erwin Frey

Dynamic heterogeneity has often been modeled by assuming that a single-particle observable, fluctuating at a molecular scale, is influenced by its coupling to environmental variables fluctuating on a second, perhaps slower, time scale.…

Condensed Matter · Physics 2009-11-07 Gregor Diezemann , Gerald Hinze , Hans Sillescu

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

Epidemic models are used to analyze the progression or outcome of an epidemic under different control policies like vaccinations, quarantines, lockdowns, use of face-masks, pharmaceutical interventions, etc. When these models accurately…

Quantitative Methods · Quantitative Biology 2022-04-19 Carlos Hernandez-Suarez , Osval Montsinos Lopez , Ramon Solano-Barajas

We study the long-time behavior of stochastic models with an absorbing state, conditioned on survival. For a large class of processes, in which saturation prevents unlimited growth, statistical properties of the surviving sample attain…

Statistical Mechanics · Physics 2009-11-07 Ronald Dickman , Ronaldo Vidigal

We examine birth--death processes with state dependent transition probabilities and at least one absorbing boundary. In evolution, this describes selection acting on two different types in a finite population where reproductive events occur…

Populations and Evolution · Quantitative Biology 2010-10-12 Philipp M. Altrock , Chaytanya S. Gokhale , Arne Traulsen

A branching random walk in presence of an absorbing wall moving at a constant velocity $v$ undergoes a phase transition as the velocity $v$ of the wall varies. Below the critical velocity $v_c$, the population has a non-zero survival…

Statistical Mechanics · Physics 2008-02-12 Damien Simon , Bernard Derrida

We consider a broad class of continuous-time two-type population size-dependent Markov Branching Processes. The offspring distribution can depend on the current (alive) and total (dead and alive) populations. Using stochastic approximation…

Probability · Mathematics 2023-04-04 Khushboo Agarwal , Veeraruna Kavitha

Dynamic processes in complex networks are crucial for better understanding collective behavior in human societies, biological systems, and the internet. In this paper, we first focus on the continuous Markov-based modeling of evolving…

Social and Information Networks · Computer Science 2025-05-21 Minyu Feng , Ziyan Zeng , Qin Li , Matjaž Perc , Jürgen Kurths

We study the long-time dynamics in non-Markovian single-population stochastic models, where one or more reactions are modelled as a stochastic process with a fat-tailed non-exponential distribution of waiting times, mimicking long-term…

Statistical Mechanics · Physics 2024-04-05 Ohad Vilk , Michael Assaf

A branching process in a Markovian environment consists of an irreducible Markov chain on a set of "environments" together with an offspring distribution for each environment. At each time step the chain transitions to a new random…

Probability · Mathematics 2021-06-22 Lila Greco , Lionel Levine

We present numerical results obtained from the modelling of a stochastic, highly connected and mobile community. The spread of attributes like health, disease among the community members is simulated using cellular automata on a planar 2…

Populations and Evolution · Quantitative Biology 2020-08-26 Ishant Tiwari , Pradeep Sarin , Punit Parmananda

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

Compartmentalization of biochemical processes underlies all biological systems, from the organelle to the tissue scale. Theoretical models to study the interplay between noisy reaction dynamics and compartmentalization are sparse, and…

Quantitative Methods · Quantitative Biology 2022-06-08 Lorenzo Duso , Christoph Zechner

A class of stochastic vector-borne infectious disease models is derived and studied. The class type is determined by a general nonlinear incidence rate of the disease. The disease spreads in a highly random environment with variability from…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

We study an epidemic model for a constant population by taking into account four compartments of the individuals characterizing their states of health. Each individual is in one of the compartments susceptible (S); incubated - infected yet…

Populations and Evolution · Quantitative Biology 2023-04-20 Teo Granger , Thomas M. Michelitsch , Michael Bestehorn , Alejandro P. Riascos , Bernard A. Collet

This study aims to estimate the parameters of a stochastic exposed-infected epidemiological model for the transmission dynamics of notifiable infectious diseases, based on observations related to isolated cases counts only. We use the…

Applications · Statistics 2024-04-15 Ibrahim Bouzalmat , Benoîte de Saporta , Solym M. Manou-Abi
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