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In this article we propose a new method, which we name 'quartet neighbor joining', or 'quartet-NJ', to infer an unrooted species tree on a given set of taxa T from empirical distributions of unrooted quartet gene trees on all four-taxon…

Populations and Evolution · Quantitative Biology 2011-08-09 Martin Kreidl

A recurring theme in the least squares approach to phylogenetics has been the discovery of elegant combinatorial formulas for the least squares estimates of edge lengths. These formulas have proved useful for the development of efficient…

Combinatorics · Mathematics 2009-11-13 Radu Mihaescu , Lior Pachter

In this paper, we propose an ensemble learning algorithm called \textit{under-bagging $k$-nearest neighbors} (\textit{under-bagging $k$-NN}) for imbalanced classification problems. On the theoretical side, by developing a new learning…

Machine Learning · Statistics 2021-09-03 Hanyuan Hang , Yuchao Cai , Hanfang Yang , Zhouchen Lin

In this paper, we will analyze the behavior of the Neighbor Joining algorithm on five taxa and we will show that the partition of the sample (data) space for estimation of a tree topology with five taxa into subspaces, within each of which…

Combinatorics · Mathematics 2007-05-23 Kord Eickmeyer , Ruriko Yoshida

The number of the non-shared edges of two phylogenies is a basic measure of the dissimilarity between the phylogenies. The non-shared edges are also the building block for approximating a more sophisticated metric called the nearest…

Data Structures and Algorithms · Computer Science 2007-05-23 Wing-Kai Hon , Ming-Yang Kao , Tak-Wah Lam , Wing-Kin Sung , Siu-Ming Yiu

UPGMA (Unweighted Pair Group Method with Arithmetic Mean) is a widely used clustering method. Here we show that UPGMA is a greedy heuristic for the normalized equidistant minimum evolution (NEME) problem, that is, finding a rooted tree that…

Populations and Evolution · Quantitative Biology 2017-04-04 Vincent Moulton , Andreas Spillner , Taoyang Wu

An algorithm is developed for finding a close to optimal junction tree of a given graph G. The algorithm has a worst case complexity O(c^k n^a) where a and c are constants, n is the number of vertices, and k is the size of the largest…

Data Structures and Algorithms · Computer Science 2013-02-18 Ann Becker , Dan Geiger

Feature correspondence selection is pivotal to many feature-matching based tasks in computer vision. Searching for spatially k-nearest neighbors is a common strategy for extracting local information in many previous works. However, there is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Chen Zhao , Zhiguo Cao , Chi Li , Xin Li , Jiaqi Yang

A central theme in phylogenetics is the reconstruction and analysis of evolutionary trees from a given set of data. To determine the optimal search methods for reconstructing trees, it is crucial to understand the size and structure of the…

Populations and Evolution · Quantitative Biology 2016-08-15 Jamie V. de Jong , Jeanette C McLeod , Mike Steel

Motivation: Navigating the high dimensional space of discrete trees for phylogenetics presents a challenging problem for tree optimisation. To address this, hyperbolic embeddings of trees offer a promising approach to encoding trees…

Populations and Evolution · Quantitative Biology 2023-09-22 Matthew Macaulay , Mathieu Fourment

Recently manifold learning algorithm for dimensionality reduction attracts more and more interests, and various linear and nonlinear, global and local algorithms are proposed. The key step of manifold learning algorithm is the neighboring…

Methodology · Statistics 2017-04-14 Lin Ma , Caifa Zhou , Xi Liu , Yubin Xu

Balanced minimum evolution is a distance-based criterion for the reconstruction of phylogenetic trees. Several algorithms exist to find the optimal tree with respect to this criterion. One approach is to minimize a certain linear functional…

Combinatorics · Mathematics 2019-05-23 Cassandra Durell , Stefan Forcey

Determining the interaction partners among protein/domain families poses hard computational problems, in particular in the presence of paralogous proteins. Available approaches aim to identify interaction partners among protein/domain…

Populations and Evolution · Quantitative Biology 2015-01-14 Iman Hajirasouliha , Alexander Schönhuth , David Juan , Alfonso Valencia , S. Cenk Sahinalp

We consider machine learning in a comparison-based setting where we are given a set of points in a metric space, but we have no access to the actual distances between the points. Instead, we can only ask an oracle whether the distance…

Machine Learning · Statistics 2017-04-06 Siavash Haghiri , Debarghya Ghoshdastidar , Ulrike von Luxburg

Manifold learning now plays a very important role in machine learning and many relevant applications. Although its superior performance in dealing with nonlinear data distribution, data sparsity is always a thorny knot. There are few…

Machine Learning · Computer Science 2019-09-17 Shenglan Liu , Yang Yu , Yang Liu , Hong Qiao , Lin Feng , Jiashi Feng

Phylogenetic trees are leaf-labelled trees, where the leaves correspond to extant species (taxa), and the internal vertices represent ancestral species. The evolutionary history of a set of species can be explained by more than one…

Data Structures and Algorithms · Computer Science 2016-09-07 Asish Mukhopadhyay , Puspal Bhabak

Distance-based approaches in phylogenetics such as Neighbor-Joining are a fast and popular approach for building trees. These methods take pairs of sequences from them construct a value that, in expectation, is additive under a stochastic…

Populations and Evolution · Quantitative Biology 2008-08-21 Mike Steel

We study the problem of maximizing a monotone submodular function with viability constraints. This problem originates from computational biology, where we are given a phylogenetic tree over a set of species and a directed graph, the…

Data Structures and Algorithms · Computer Science 2016-11-18 Wolfgang Dvořák , Monika Henzinger , David P. Williamson

In this paper we present the first provable approximate nearest-neighbor (ANN) algorithms for Bregman divergences. Our first algorithm processes queries in O(log^d n) time using O(n log^d n) space and only uses general properties of the…

Computational Geometry · Computer Science 2013-09-17 Amirali Abdullah , John Moeller , Suresh Venkatasubramanian

Matching datasets of multiple modalities has become an important task in data analysis. Existing methods often rely on the embedding and transformation of each single modality without utilizing any correspondence information, which often…

Machine Learning · Statistics 2024-06-27 Cencheng Shen , Joshua T. Vogelstein , Carey E. Priebe