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Related papers: Non-linear mechanical response of the Red Blood Ce…

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Blood rheology and microcirculation are strongly influenced by red blood cell aggregation. We investigate the dissociation rates of red cell aggregates in extensional flow using hyperbolic microfluidic constrictions and image analysis by a…

Biological Physics · Physics 2024-07-30 Midhun Puthumana Melepattu , Guillaume Maitrejean , Thomas Podgorski

The mechanical properties of cells are dominated by the cytoskeleton, an interconnected network of long elastic filaments. The connections between the filaments are provided by crosslinking proteins, which constitute, next to the filaments,…

Soft Condensed Matter · Physics 2012-10-09 Claus Heussinger

We introduce a strain-energy based nonlinear hyper-elastic formulation to model the material properties of ultrasoft dielectric elastomers over a wide range of elastic properties, prestretch, and thicknesses. We build on the uniaxial Gent…

Materials Science · Physics 2020-06-24 Asimanshu Das , Kenneth S. Breuer , Varghese Mathai

The autocorrelation function in many complex systems shows a crossover in the form of its decay: from stretched exponential relaxation (SER) at short times to power law at long times. Studies of the mechanisms leading to such multiple…

Statistical Mechanics · Physics 2024-02-20 Sukanta Mukherjee , Puneet Pareek , Mustansir Barma , Saroj Kumar Nandi

In this paper, we seek to model the deformation of nucleated cells by single diode-laser bar optical stretchers. We employ a recently developed computational model, the Dynamic Ray-Tracing method, to determine the stress distribution…

Biological Physics · Physics 2015-01-16 Ihab Sraj , Joshua Francois , David W. M. Marr , Charles D. Eggleton

Understanding the rheological properties of soft biological tissue is a key issue for mechanical systems used in the healthcare field. We propose a simple empirical model using Fractional Dynamics and Exponential Nonlinearity (FDEN) to…

Biological Physics · Physics 2025-03-26 Yo Kobayashi , Mariko Tsukune , Tomoyuki Miyashita , Masakatsu G. Fujie

We use optical tweezers microrheology and fluorescence microscopy to apply nonlinear microscale strains to entangled and crosslinked actin networks, and measure the resulting stress and actin filament deformations. We couple nonlinear…

Soft Condensed Matter · Physics 2016-10-24 Bekele Gurmessa , Shea Ricketts , Rae M. Robertson-Anderson

We study the mechanical response of an open cell dry foam subjected to periodic forcing using experiments and theory. Using the measurements of the static and dynamic stress-strain relationship, we derive an over-damped model of the foam,…

Soft Condensed Matter · Physics 2012-10-24 Buddhapriya Chakrabarti , Peter J. Hine , B. M. A. G. Piette

To produce sounds, we adjust the tension of our vocal folds to shape their properties and control the pitch. This efficient mechanism offers inspiration for designing reconfigurable materials and adaptable soft robots. However,…

Soft Condensed Matter · Physics 2025-06-18 Alexandre Delory , Daniel A. Kiefer , Maxime Lanoy , Antonin Eddi , Claire Prada , Fabrice Lemoult

The dynamical mechanical analysis of blood generally uses models inspired by conventional flows, assuming scale-independent homogeneous flows and without considering fluid-surface boundary interactions. The present experimental study…

Fluid Dynamics · Physics 2024-09-24 Ursula Windberger , Patrick Baroni , Laurence Noirez

The shear response of soft solids can be modeled with linear elasticity, provided the forcing is slow and weak. Both of these approximations must break down when the material loses rigidity, such as in foams and emulsions at their…

Soft Condensed Matter · Physics 2016-07-06 Julia Boschan , Daniel Vagberg , Ellak Somfai , Brian P. Tighe

Local stresses in a tissue, a collective property, regulate cell division and apoptosis. In turn, cell growth and division induce active stresses in the tissue. As a consequence, there is a feedback between cell growth and local stresses.…

Soft Condensed Matter · Physics 2024-05-06 Sumit Sinha , Xin Li , Abdul N Malmi-Kakkada , D. Thirumalai

Cell migration plays a fundamental role in numerous physiological processes, including embryonic development, wound healing, and cancer metastasis. While cell-cell adhesion is known to regulate motion by shaping cell morphology and…

Biological Physics · Physics 2026-03-09 Anh Q. Nguyen , Pradip K. Bera , Jacob Notbohm , Dapeng Bi

Networks of filamentous proteins play a crucial role in cell mechanics. These cytoskeletal networks, together with various crosslinking and other associated proteins largely determine the (visco)elastic response of cells. In this letter we…

Disordered Systems and Neural Networks · Physics 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh

In tissue development, wound healing, and cancer invasion, coordinated cell motion arises from active forces produced by the cells. The relationship between force and motion remains unclear, however, because the forces result from a sum of…

Biological Physics · Physics 2025-12-17 Molly McCord , Jacob Notbohm

Due to the potential impact on the diagnosis and treatment of various cardiovascular diseases, work on the rheology of blood has significantly expanded in the last decade, both experimentally and theoretically. Experimentally, blood has…

Soft Condensed Matter · Physics 2021-11-08 Antony N. Beris , Jeffrey S. Horner , Soham Jariwala , Mathew J. Armstrong , Norman J. Wagner

The connection between the properties of cell tissue and those of the single constituent cells remains to be elucidated. At the purely mechanical level, the degree of rigidity of different cellular components, such as the nucleus and the…

Soft Condensed Matter · Physics 2022-03-15 Stefano Villa , Andrea Palamidessi , Emanuela Frittoli , Giorgio Scita , Roberto Cerbino , Fabio Giavazzi

The mechanical behaviour of solid biological tissues has long been described using models based on classical continuum mechanics. However, the classical continuum theories of elasticity and viscoelasticity cannot easily capture the…

Biological Physics · Physics 2017-05-16 Shakti N. Menon , Cameron L. Hall , Scott W. McCue , D. L. Sean McElwain

Cell mechanical functions like locomotion, contraction and division are controlled by the cytoskeleton, a dynamic biopolymer network whose mechanical properties remain poorly understood. We perform single-cell uniaxial stretching…

Biological Physics · Physics 2007-05-23 Pablo Fernandez , Pramod A. Pullarkat , Albrecht Ott

We study model near-critical polymer gelling systems made of gluten proteins dispersions stabilized at different distances from the gel point. We impose different shear rates and follow the time evolution of the stress. For sufficiently…

Soft Condensed Matter · Physics 2024-07-18 Ameur Louhichi , Marie-Hélène Morel , Laurence Ramos , Amélie Banc