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Optical tweezers are powerful tools for high resolution study of surface properties. Such experiments are traditionally performed by studying the active or the brownian fluctuation of trapped particles in the X, Y, Z direction. Here we find…

Optics · Physics 2018-11-13 Rahul Vaipully , Dhanush Bhatt , Anand Dev Ranjan , Basudev Roy

Using Monte Carlo simulations, we study the hysteresis in unzipping of a double stranded block copolymer DNA with $-A_n B_n-$ repeat units. Here $A$ and $B$ represent two different types of base pairs having two- and three-bonds,…

Soft Condensed Matter · Physics 2021-01-27 Ramu Kumar Yadav , Rajeev Kapri

The control over DNA elongation in nanofluidic devices holds great potential for large-scale genomic analysis. So far, the manipulation of DNA in nanochannels has been mostly carried out with electrophoresis and seldom with hydrodynamics,…

It is known that line optical tweezers (LOT) can measure potential of mean force (PMF) between colloidal particles in the bulk. However, PMF obtained with LOT is empirically modified before showing the result of the final form in order to…

Soft Condensed Matter · Physics 2025-07-28 Ken-ichi Amano , Rikako Suzuki , Madoka Takasu

Novel approaches to DNA sequencing and detection require the measurement of electrical currents between metal probes immersed in ionic solution. Here, we experimentally demonstrate that these systems maintain large background currents with…

Brushes formed by arm-tethered starlike polyelectrolytes may exhibit internal segregation into weakly and strongly extended populations (stratified two-layer structure) when strong ionic intermolecular repulsions induce stretching of the…

The chiral nature of DNA plays a crucial role in cellular processes. Here we use magnetic tweezers to explore one of the signatures of this chirality, the coupling between stretch and twist deformations. We show that the extension of a…

Biomolecules · Quantitative Biology 2009-09-29 Timothee Lionnet , Sylvain Joubaud , Richard Lavery , David Bensimon , Vincent Croquette

The response of a semiflexible polyelectrolyte chain to stretching in the regimes of moderate and weak screening is studied theoretically, with a special focus on DNA experiments. By using the nonlinear Poisson--Boltzmann description of…

Soft Condensed Matter · Physics 2007-05-23 Alexei V. Tkachenko

A coarse grained model for flexible polymers end-grafted to repulsive spherical nanoparticles is studied for various chain lengths and grafting densities under good solvent conditions, by Molecular Dynamics methods and density functional…

Soft Condensed Matter · Physics 2015-05-18 Federica Lo Verso , Sergei A. Egorov , Andrey Milchev , Kurt Binder

DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function. To fully understand this molecular heterogeneity, DNA and…

Biomolecules · Quantitative Biology 2015-04-15 Adam J. M. Wollman , Helen Miller , Zhaokun Zhou , Mark C. Leake

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

Soft Condensed Matter · Physics 2008-02-03 C. S. O'Hern , Randall D. Kamien , T. C. Lubensky , Philip Nelson

Debates about conductivity of DNAs have been recently renewed due to contradictory results of direct measurements by use of electrical contacts to molecules. In several works it was discovered that double-stranded (ds)DNAs are conductors:…

Condensed Matter · Physics 2007-05-23 A. Yu. Kasumov , D. V. Klinov

We propose a new strategy to improve the self-assembly properties of DNA-functionalised colloids. The problem that we address is that DNA-functionalised colloids typically crystallize in a narrow temperature window, if at all. The…

Soft Condensed Matter · Physics 2013-01-22 B. M. Mognetti , M. E. Leunissen , D. Frenkel

The translocation of double-stranded DNA through a solid-state nanopore may either decrease or increase the ionic current depending on the ionic concentration of the surrounding solution. Below a certain crossover ionic concentration, the…

Biological Physics · Physics 2019-09-04 Vivian Wang , Niklas Ermann , Ulrich F. Keyser

Single molecule DNA experiments often generate data from force versus extension measurements involving the tethering of a microsphere to one end of a single DNA molecule while the other is attached to a substrate. We show that the…

Biological Physics · Physics 2015-06-26 Jose Coelho Neto , Ronald Dickman , O. N. Mesquita

Interactions between silica surfaces across isopropanol solutions are measured with colloidal probe technique based on atomic force microscope. In particular, the influence of 1:1 electrolytes on the interactions between silica particles is…

Soft Condensed Matter · Physics 2020-07-01 Biljana Stojimirovic , Marco Galli , Gregor Trefalt

Optical fields can induce forces between microscopic objects, thus giving rise to new structures of matter. We study theoretically these optical forces between two spheres, either isolated in water, or in presence of a flat dielectric…

Optics · Physics 2009-11-10 P. C. Chaumet , M. Nieto-Vesperinas

Precise measuring the deforming force and observation of the deformation dynamics along with difficulties of micro sample preparation are the main problems which make the micro-scale experiments difficult. Here we present a method for…

Soft Condensed Matter · Physics 2015-06-23 Sasun G. Gevorkian , Artashes V. Karmenyan , Chin-Kun Hu

Optical tweezers are a powerful tool for the precise positioning of a variety of small objects, including single neutral atoms. Once trapped, atoms can be cooled to the motional ground state of the tweezers. For a more advanced control of…

In this paper, we study electrostatic and structural properties between pH-responsive polyelectrolyte brushes by using a strong stretching theory accounting for excluded volume interactions, the density of polyelectrolyte chargeable sites…

Soft Condensed Matter · Physics 2022-08-31 Jun-Sik Sin