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Proton transfer across single layer graphene is associated with large computed energy barriers and is therefore thought to be unfavorable at room temperature unless nanoscale holes or dopants are introduced, or a potential bias is applied.…

Why is the genetic code the way it is? The most successful theory states that the codon assignments minimise the effects of errors arising in primordial living systems. Here a transversion is reported that leaves invariant degeneracy in the…

Biological Physics · Physics 2007-05-23 Jean-Luc Jestin

The biological world, especially its majority microbial component, is strongly interacting and may be dominated by collective effects. In this review, we provide a brief introduction for statistical physicists of the way in which living…

Populations and Evolution · Quantitative Biology 2015-05-20 Nicholas Chia , Nigel Goldenfeld

It is proposed that the co-expression of statistically significant motifs among the sequences of a proteome is a phylogenetic trait. From the co-expression matrix of such motifs in a group of prokaryotic proteomes a suitable definition of a…

Molecular Networks · Quantitative Biology 2007-05-23 Luca Ferraro , Andrea Giansanti , Giovanni Giuliano , Vittorio Rosato

We investigate the distribution of flavonoids, a major category of plant secondary metabolites, across species. Flavonoids are known to show high species specificity, and were once considered as chemical markers for understanding adaptive…

Molecular Networks · Quantitative Biology 2009-04-23 Kazuhiro Takemoto , Masanori Arita

We investigate critical behaviors of a social contagion model on weighted networks. An edge-weight compartmental approach is applied to analyze the weighted social contagion on strongly heterogenous networks with skewed degree and weight…

Physics and Society · Physics 2017-07-12 Yu-Xiao Zhu , Wei Wang , Ming Tang , Yong-Yeol Ahn

It is a well-known fact that genetic sequences may contain sections with repeated units, called repeats, that differ in length over a population, with a length distribution of geometric type. A simple class of recombination models with…

Dynamical Systems · Mathematics 2010-02-09 Michael Baake

So far mutations analysis was performed in terms of transitions and trasversions, so on the basis of the molecule, or in terms of GC-content and isochors, through the quantification of GC->AT mutations over AT->GC mutations. We tried a…

Other Quantitative Biology · Quantitative Biology 2014-11-19 Valentina Agoni

Transfer learning (TL) is used to extrapolate the physics information encoded in a Generative Adversarial Network (GAN) trained on synthetic neutrino-carbon inclusive scattering data to related processes such as neutrino-argon and…

High Energy Physics - Phenomenology · Physics 2026-03-20 Jose L. Bonilla , Krzysztof M. Graczyk , Artur M. Ankowski , Rwik Dharmapal Banerjee , Beata E. Kowal , Hemant Prasad , Jan T. Sobczyk

There is growing evidence that pretrained language models improve task-specific fine-tuning not just for the languages seen in pretraining, but also for new languages and even non-linguistic data. What is the nature of this surprising…

Computation and Language · Computer Science 2021-04-20 Zhengxuan Wu , Nelson F. Liu , Christopher Potts

This paper presents and compares alternative transfer learning methods that can increase the power of conditional testing via knockoffs by leveraging prior information in external data sets collected from different populations or measuring…

Applications · Statistics 2021-08-20 Shuangning Li , Zhimei Ren , Chiara Sabatti , Matteo Sesia

Motivated by novel results in the theory of correlated sequences, we analyze the dynamics of random walks with long-term memory (binary chains with long-range correlations). In our model, the probability for a unit bit in a binary string…

Statistical Mechanics · Physics 2009-11-10 Shahar Hod , Uri Keshet

Transposable elements (TEs) constitute a significant portion of eukaryotic genomes, yet their role in chromatin organization remains poorly understood. This study investigates the distribution patterns of TEs around chromatin ligation…

Other Quantitative Biology · Quantitative Biology 2024-08-22 Alexandr V. Vikhorev , Michael M. Rempel , Oksana O. Polesskaya , Ivan V. Savelev , Max V. Myakishev-Rempel

Gene expression is a complex and quantitative trait that is influenced by both genetic and non-genetic regulators including environmental factors. Evaluating the contribution of environment to gene expression regulation and identifying…

Genomics · Quantitative Biology 2019-06-27 Ke Tang , Wei Zhang

An approach for approximately calculating the number of genes in a genome is presented, which takes into account the average protein length expected for the species. A number of virus, bacterial and eukaryotic genomes are scrutinized.…

Genomics · Quantitative Biology 2015-02-13 N. S. Santos-Magalhaes , H. M. de Oliveira

With the development of high throughput sequencing technology, it becomes possible to directly analyze mutation distribution in a genome-wide fashion, dissociating mutation rate measurements from the traditional underlying assumptions.…

Genomics · Quantitative Biology 2015-05-14 D. Parkhomchuk , V. S. Amstislavskiy , A. Soldatov , V. Ogryzko

We updated the agent based Monte Carlo code HERITAGE that simulates human evolution within restrictive environments such as interstellar, sub-light speed spacecraft in order to include the effects of population genetics. We incorporated a…

Popular Physics · Physics 2021-02-03 F. Marin , C. Beluffi , F. Fischer

In this work, charge transport (CT) properties of the p53 gene are numerically studied by the transfer matrix method, and using either single or double strand effective tight-binding models. A statistical analysis of the consequences of…

Genomics · Quantitative Biology 2007-10-10 Chi-Tin Shih , Rudolf A. Römer , Stephan Roche

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

Genetic association analyses often involve data from multiple potentially-heterogeneous subgroups. The expected amount of heterogeneity can vary from modest (e.g., a typical meta-analysis) to large (e.g., a strong gene--environment…

Methodology · Statistics 2014-04-15 Xiaoquan Wen , Matthew Stephens
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