Repeat distributions from unequal crossovers
Abstract
It is a well-known fact that genetic sequences may contain sections with repeated units, called repeats, that differ in length over a population, with a length distribution of geometric type. A simple class of recombination models with single crossovers is analysed that result in equilibrium distributions of this type. Due to the nonlinear and infinite-dimensional nature of these models, their analysis requires some nontrivial tools from measure theory and functional analysis, which makes them interesting also from a mathematical point of view. In particular, they can be viewed as quadratic, hence nonlinear, analogues of Markov chains.
Cite
@article{arxiv.0803.1270,
title = {Repeat distributions from unequal crossovers},
author = {Michael Baake},
journal= {arXiv preprint arXiv:0803.1270},
year = {2010}
}
Comments
18 pages, 1 figure; introductory survey, presented at the summer school `Statistical Models in Biological Sciences' (Banach Center, Warszawa, 2006)