Related papers: Schizophrenia - a parameters' game?
Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…
Clinical practice in psychiatry is burdened with the increased demand for healthcare services and the scarce resources available. New paradigms of health data powered with machine learning techniques could open the possibility to improve…
We have reported nanometer-scale three-dimensional studies of brain networks of schizophrenia cases and found that their neurites are thin and tortuous compared to healthy controls. This suggests that connections between distal neurons are…
Automated classification methods for disease diagnosis are currently in the limelight, especially for imaging data. Classification does not fully meet a clinician's needs, however: in order to combine the results of multiple tests and…
Parkinson's disease (PD) is a neurodegenerative disorder characterized by increased response times leading to a variety of biomechanical symptoms such as tremors, stooping and gait instability. Although the deterioration in biomechanical…
Natural language processing tools are used to automatically detect disturbances in transcribed speech of schizophrenia inpatients who speak Hebrew. We measure topic mutation over time and show that controls maintain more cohesive speech…
In recent years, there is strong emphasis on mining medical data using machine learning techniques. A common problem is to obtain a noiseless set of textual documents, with a relevant content for the research question, and developing a…
This systematic review assessed the current state and future prospects of artificial intelligence (AI) in schizophrenia rehabilitation management. We reviewed 61 studies on AI-related data types, feature engineering methods, algorithmic…
Mental disorders are among the leading causes of disability worldwide. The first step in treating these conditions is to obtain an accurate diagnosis, but the absence of established clinical tests makes this task challenging. Machine…
A general dynamical process model of psychiatric disorders is proposed that specifies the basic cognitive processes involved in the transition from beliefs about self, others and world that are normal and adaptive, to beliefs that are…
Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently…
Background: The choice of efficient antipsychotic therapy for schizophrenia relies on a time-consuming trial-and-error approach, whereas the social and economic burdens of the disease call for faster alternatives. Material \& methods: In a…
As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The…
Redundancy is a ubiquitous property of the nervous system. This means that vastly different configurations of cellular and synaptic components can enable the same neural circuit functions. However, until recently very little brain disorder…
Introduction Schizophrenia is a severe mental disorder, and early diagnosis is key to improving outcomes. Its complexity makes predicting onset and progression challenging. EEG has emerged as a valuable tool for studying schizophrenia, with…
Background: The precise quantification of negative symptoms is necessary to improve differential diagnosis and prognosis prediction in Schizophrenia. In chronic psychotic patients, the representation of verbal reports as word graphs…
Serious games have proven to be effective tools for screening cognitive impairments and supporting diagnosis in patients with neurodegenerative diseases like Alzheimer's and Parkinson's. They also offer cognitive training benefits.…
The present review presents multiple techniques in which ocular assessments may serve as a noninvasive approach for the early diagnoses of various cognitive and psychiatric disorders, such as Alzheimer's disease (AD), autism spectrum…
Schizophrenia is a complicated mental illness characterized by a broad spectrum of symptoms affecting cognition, behavior, and emotion. The task of identifying reliable biomarkers to classify Schizophrenia accurately continues to be a…
Finding general principles underlying brain function has been appealing to scientists. Indeed, in some branches of science like physics and chemistry (and to some degree biology) a general theory often can capture the essence of a wide…