Related papers: Schizophrenia - a parameters' game?
Controllability properties are studied for control-affine systems depending on a parameter and with constrained control values. The uncontrolled systems in dimension two and three are subject to a homoclinic bifurcation. This generates two…
Introduction. Increased efforts in neuroscience try to understand mental disorders as brain disorders. In the present study we investigate how common a neuroreductionist inclination is among highly educated people. In particular, we shed…
In recent years, the field of neuroscience has gone through rapid experimental advances and a significant increase in the use of quantitative and computational methods. This growth has created a need for clearer analyses of the theory and…
The mechanisms underlying major aspects of the human brain remain a mystery. It is unknown how verbal episodic memory is formed and integrated with sensory episodic memory. There is no consensus on the function and nature of dreaming. Here…
This study quantifies the association between non-adherence to antipsychotic medications and adverse outcomes in individuals with schizophrenia. We frame the problem using survival analysis, focusing on the time to the earliest of several…
In this paper, we characterize major depression (MD) as a complex dynamical system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be…
The use of Artificial Intelligence is finding prominence not only in core computer areas, but also in cross disciplinary areas including medical diagnosis. In this paper, we present a rule based Expert System used in diagnosis of Cerebral…
Diabetic neuropathy is a disorder characterized by impaired nerve function and reduction of the number of epidermal nerve fibers per epidermal surface. Additionally, as neuropathy related nerve fiber loss and regrowth progresses over time,…
Borderline personality disorder and narcissistic personality disorder are important nosographic entities and have been subject of intensive investigations. The currently prevailing psychodynamic theory for mental disorders is based on the…
The great behavioral heterogeneity observed between individuals with the same psychiatric disorder and even within one individual over time complicates both clinical practice and biomedical research. However, modern technologies are an…
This paper describes a novel approach to medical diagnosis based on the SP theory of computing and cognition. The main attractions of this approach are: a format for representing diseases that is simple and intuitive; an ability to cope…
Assessing the causal effects of interventions on ordinal outcomes is an important objective of many educational and behavioral studies. Under the potential outcomes framework, we can define causal effects as comparisons between the…
A mental health disorder is a clinically significant impairment in a persons intellect, emotional control, or behavior. Mental disorders and outpatient morbidity are a challenge to public health in Kenya. The spatial distribution and study…
Influenza is an acute respiratory infection caused by a virus. It is highly contagious and rapidly mutative. However, its epidemiological characteristics are conventionally collected in terms of outpatient records. In fact, the subjective…
The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often…
The field of serious games for health has grown significantly, demonstrating effectiveness in various clinical contexts such as stroke, spinal cord injury, and degenerative neurological diseases. Despite their potential benefits, therapists…
Disorganized thinking is a key diagnostic indicator of schizophrenia-spectrum disorders. Recently, clinical estimates of the severity of disorganized thinking have been shown to correlate with measures of how difficult speech transcripts…
Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…
Brain functional connectivity alterations, that is, pathological changes in the signal exchange between areas of the brain, occur in several neurological diseases, including neurodegenerative and neuropsychiatric ones. They consist in…
A biological understanding is key for managing medical conditions, yet psychological and social aspects matter too. The main problem is that these two aspects are hard to quantify and inherently difficult to communicate. To quantify…