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Configurational entropy is an important factor in the free energy change of many macromolecular recognition and binding processes, and has been intensively studied. Despite great progresses that have been made, the global sampling remains…

Biological Physics · Physics 2012-12-04 Wenzhao Li , Kai Wang , Suyan Tian , Pu Tian

We propose to examine the predictability and the complexity characteristics of the Standard&Poor500 dynamics behaviors in a coarse-grained way using the symbolic dynamics method and under the prism of the Information theory through the…

Statistical Finance · Quantitative Finance 2021-05-11 Geoffrey Ducournau

One of the central challenges in modern machine learning is understanding how neural networks generalize knowledge learned from training data to unseen test data. While numerous empirical techniques have been proposed to improve…

Machine Learning · Computer Science 2025-04-18 Entao Yang , Xiaotian Zhang , Yue Shang , Ge Zhang

Boolean Networks (BNs) serve as a fundamental modeling framework for capturing complex dynamical systems across various domains, including systems biology, computational logic, and artificial intelligence. A crucial property of BNs is the…

Logic in Computer Science · Computer Science 2025-06-19 Mohimenul Kabir , Van-Giang Trinh , Samuel Pastva , Kuldeep S Meel

This short paper presents an abstract, tunable model of genomic structural change within the cell lifecycle and explores its use with simulated evolution. A well-known Boolean model of genetic regulatory networks is extended to include…

Computational Engineering, Finance, and Science · Computer Science 2012-01-18 Larry Bull

The entropy of a hierarchical network topology in an ensemble of sparse random networks with "hidden variables" associated to its nodes, is the log-likelihood that a given network topology is present in the chosen ensemble.We obtain a…

Disordered Systems and Neural Networks · Physics 2009-11-13 Ginestra Bianconi , Anthony C. C. Coolen , Conrad J. Perez Vicente

Entropy has emerged as a dynamic, interdisciplinary, and widely accepted quantitative measure of uncertainty across different disciplines. A unified understanding of entropy measures, supported by a detailed review of their theoretical…

Probability · Mathematics 2025-03-21 Naveen Kumar , Ambesh Dixit , Vivek Vijay

Complex systems are characterised by a tight, nontrivial interplay of their constituents, which gives rise to a multi-scale spectrum of emergent properties. In this scenario, it is practically and conceptually difficult to identify those…

Statistical Mechanics · Physics 2022-10-19 Roi Holtzman , Marco Giulini , Raffaello Potestio

Entanglement is a key quantum phenomena and understanding transitions between phases of matter with different entanglement properties are an interesting probe of quantum mechanics. We numerically study a model of a 2D tensor network…

Statistical Mechanics · Physics 2021-08-06 Ryan Levy , Bryan K. Clark

Here we present the entropic dynamics formalism for networks. That is, a framework for the dynamics of graphs meant to represent a network derived from the principle of maximum entropy and the rate of transition is obtained taking into…

Physics and Society · Physics 2021-04-29 Felipe Xavier Costa , Pedro Pessoa

Complex networks describe a wide range of systems in nature and society, much quoted examples including the cell, a network of chemicals linked by chemical reactions, or the Internet, a network of routers and computers connected by physical…

Statistical Mechanics · Physics 2016-08-31 Reka Albert , Albert-Laszlo Barabasi

Inferring dynamic biochemical networks is one of the main challenges in systems biology. Given experimental data, the objective is to identify the rules of interaction among the different entities of the network. However, the number of…

Commutative Algebra · Mathematics 2012-07-31 Franziska Hinkelmann , Abdul Salam Jarrah

Boolean networks are a valuable class of discrete dynamical systems models, but they remain fundamentally limited by their inability to capture multi-way interactions in their components. To remedy this limitation, we propose a model of…

Dynamical Systems · Mathematics 2024-09-02 Kevin M. Stoltz , Cliff A. Joslyn

Despite the large quantity of information available, thorough researches in various biological databases are still needed in order to reconstruct and understand the steps that lead to known or new phenomena. By using protein-protein…

Molecular Networks · Quantitative Biology 2014-12-03 Alberto Calderone

The relationship between the properties of a dynamical system and the structure of its defining equations has long been studied in many contexts. Here we study this problem for the class of conjunctive (resp. disjunctive) Boolean networks,…

Combinatorics · Mathematics 2008-05-13 Abdul Salam Jarrah , Reinhard Laubenbacher , Alan Veliz-Cuba

The dynamics of noise-resilient Boolean networks with majority functions and diverse topologies is investigated. A wide class of possible topological configurations is parametrized as a stochastic blockmodel. For this class of networks, the…

Disordered Systems and Neural Networks · Physics 2012-01-11 Tiago P. Peixoto

In this paper we present a rigorous analysis of a class of coupled dynamical systems in which two distinct types of components, one excitatory and the other inhibitory, interact with one another. These network models are finite in size but…

Dynamical Systems · Mathematics 2022-01-19 Matteo Tanzi , Lai-Sang Young

Regulatory gene networks contain generic modules like those involving feedback loops, which are essential for the regulation of many biological functions. We consider a class of self-regulated genes which are the building blocks of many…

Subcellular Processes · Quantitative Biology 2008-10-02 Thomas Fournier , Jean-Pierre Gabriel , Christian Mazza , Jerome Pasquier , Jose Galbete , Nicolas Mermod

Inferring models, predicting the future, and estimating the entropy rate of discrete-time, discrete-event processes is well-worn ground. However, a much broader class of discrete-event processes operates in continuous-time. Here, we provide…

Statistical Mechanics · Physics 2020-05-11 S. E. Marzen , J. P. Crutchfield

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. We here derive an expression for the number of attractors in…

Molecular Networks · Quantitative Biology 2007-05-23 Björn Samuelsson , Carl Troein