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We investigate the evolution of Boolean networks subject to a selective pressure which favors robustness against noise, as a model of evolved genetic regulatory systems. By mapping the evolutionary process into a statistical ensemble and…

Disordered Systems and Neural Networks · Physics 2012-04-11 Tiago P. Peixoto

The concept of robustness of regulatory networks has been closely related to the nature of the interactions among genes, and the capability of pattern maintenance or reproducibility. Defining this robustness property is a challenging task,…

Molecular Networks · Quantitative Biology 2007-10-24 Madalena Chave , Eduardo D. Sontag , Anirvan M. Sengupta

We consider discrete stochastic processes, modeled by classical master equations, on networks. The temporal growth of the lack of information about the system is captured by its non-equilibrium entropy, defined via the transition…

Statistical Mechanics · Physics 2017-04-26 Oliver Muelken , Sarah Heinzelmann , Maxim Dolgushev

As a discrete approach to genetic regulatory networks, Boolean models provide an essential qualitative description of the structure of interactions among genes and proteins. Boolean models generally assume only two possible states…

Molecular Networks · Quantitative Biology 2007-05-23 Madalena Chaves , Eduardo D. Sontag , Reka Albert

Random Boolean networks (RBNs) have been a popular model of genetic regulatory networks for more than four decades. However, most RBN studies have been made with random topologies, while real regulatory networks have been found to be…

Cellular Automata and Lattice Gases · Physics 2015-03-17 Rodrigo Poblanno-Balp , Carlos Gershenson

In this paper we revisit the concept of mobility entropy. Over time, the structure of spatial interactions among urban centres tends to become more complex and evolves from centralised models to more scattered origin and destination…

Physics and Society · Physics 2021-06-30 Valentina Marin , Carlos Molinero , Elsa Arcaute

The basin entropy is a simple idea that aims to measure the the final state unpredictability of multistable systems. Since 2016, the basin entropy has been widely used in different contexts of physics, from cold atoms to galactic dynamics.…

Chaotic Dynamics · Physics 2023-02-03 Alvar Daza , Alexandre Wagemakers , Miguel A. F. Sanjuán

Entropy is a fundamental concept in the field of information theory. During measurement, conventional entropy measures are susceptible to length and amplitude changes in time series. A new entropy metric, neural network entropy (NNetEn),…

Machine Learning · Computer Science 2023-02-14 Hanif Heidari , Andrei Velichko , Murugappan Murugappan , Muhammad E. H. Chowdhury

The existence of the {\em typical set} is key for data compression strategies and for the emergence of robust statistical observables in macroscopic physical systems. Standard approaches derive its existence from a restricted set of…

Statistical Mechanics · Physics 2022-02-10 Rudolf Hanel , Bernat Corominas-Murtra

Boolean networks have long been used as models of molecular networks and play an increasingly important role in systems biology. This paper describes a software package, Polynome, offered as a web service, that helps users construct Boolean…

We propose that chaotic Glass networks (a class of piecewise-linear Ordinary Differential Equations) are good candidates for the design of true random number generators. A Glass network design has the advantage of involving only standard…

Dynamical Systems · Mathematics 2025-02-14 Benjamin W. Wild , Roderick Edwards

The quantification of the complexity of networks is, today, a fundamental problem in the physics of complex systems. A possible roadmap to solve the problem is via extending key concepts of information theory to networks. In this paper we…

Disordered Systems and Neural Networks · Physics 2015-05-13 Kartik Anand , Ginestra Bianconi

This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model. Often Boolean models are much simpler to understand than complex…

Molecular Networks · Quantitative Biology 2011-05-10 Franziska Hinkelmann , Reinhard Laubenbacher

The structure entropy is one of the most important parameters to describe the structure property of the complex networks. Most of the existing struc- ture entropies are based on the degree or the betweenness centrality. In order to describe…

Social and Information Networks · Computer Science 2014-11-25 Qi Zhang , Xi Lu , Meizhu Li , Yong Deng , Sankaran Mahadevan

This is the second paper of a series of two about the structural properties that influence the asymptotic dynamics of Random Boolean Networks. Here we study the functionally independent clusters in which the relevant elements, introduced…

Disordered Systems and Neural Networks · Physics 2009-10-30 U. Bastolla , G. Parisi

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

Boolean automata networks (aka Boolean networks) are space-time discrete dynamical systems, studied as a model of computation and as a representative model of natural phenomena. A collection of simple entities (the automata) update their…

Discrete Mathematics · Computer Science 2024-02-12 Kévin Perrot , Sylvain Sené , Léah Tapin

Fluctuations in parameters that are typically treated as fixed play a crucial role in the behavior of complex systems. However, to date, we lack a general non-equilibrium thermodynamic treatment of such a complex system. In this Letter, to…

Statistical Mechanics · Physics 2026-03-31 Tuan Pham , Deepak Gupta

Accurate and timely detection of cyber threats is critical to keeping our online economy and data safe. A key technique in early detection is the classification of unusual patterns of network behaviour, often hidden as low-frequency events…

Cryptography and Security · Computer Science 2024-05-01 Anthony Kenyon , Lipika Deka , David Elizondo

Methods of modeling cellular regulatory networks as diverse as differential equations and Boolean networks co-exist, however, without any closer correspondence to each other. With the example system of the fission yeast cell cycle control…

Molecular Networks · Quantitative Biology 2015-03-13 Maria Davidich , Stefan Bornholdt
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