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At the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis…

Neurons and Cognition · Quantitative Biology 2009-12-18 Hugo Gabriel Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

The existence of power-law distributions is only a first requirement in the validation of the critical behavior of a system. Long-range spatio-temporal correlations are fundamental for the spontaneous neuronal activity to be the expression…

Statistical Mechanics · Physics 2018-11-27 Fabrizio Lombardi , Hans J. Herrmann , L. de Arcangelis

Single trial analyses of ensemble activity in alert animals demonstrate that cortical circuits dynamics evolve through temporal sequences of metastable states. Metastability has been studied for its potential role in sensory coding, memory…

Neurons and Cognition · Quantitative Biology 2016-03-23 Luca Mazzucato , Alfredo Fontanini , Giancarlo La Camera

Stimulus from the environment that guides behavior and informs decisions is encoded in the firing rates of neural populations. Each neuron in the populations, however, does not spike independently: spike events are correlated from cell to…

Neurons and Cognition · Quantitative Biology 2012-07-24 Nicholas Cain , Eric Shea-Brown

Neuronal avalanches, measured in vitro and in vivo, exhibit a robust critical behaviour. Their temporal organization hides the presence of correlations. Here we present experimental measurements of the waiting time distribution between…

Neurons and Cognition · Quantitative Biology 2012-04-30 F. Lombardi , H. J. Herrmann , C. Perrone-Capano , D. Plenz , L. de Arcangelis

Neuronal networks are controlled by a combination of the dynamics of individual neurons and the connectivity of the network that links them together. We study a minimal model of the preBotzinger complex, a small neuronal network that…

Neurons and Cognition · Quantitative Biology 2013-05-29 David J. Schwab , Robijn F. Bruinsma , Alex J. Levine

Several firing patterns experimentally observed in neural populations have been successfully correlated to animal behavior. Population bursting, hereby regarded as a period of high firing rate followed by a period of quiescence, is…

Cell Behavior · Quantitative Biology 2015-05-19 Anca Radulescu

We study numerically and analytically first- and second-order phase transitions in neuronal networks stimulated by shot noise (a flow of random spikes bombarding neurons). Using an exactly solvable cortical model of neuronal networks on…

Neurons and Cognition · Quantitative Biology 2015-08-25 K. -E. Lee , M. A. Lopes , J. F. F. Mendes , A. V. Goltsev

A salient feature of prefrontal cortex organization is the vast diversity of cell types that support the temporal integration of events required for sculpting future responses. A major obstacle in understanding the routing of information…

Neurons and Cognition · Quantitative Biology 2012-04-04 Michael V. Baratta , Shinya Nakamura , Peter Dobelis , Matthew B. Pomrenze , Samuel D. Dolzani , Donald C. Cooper

Living neuronal networks in dissociated neuronal cultures are widely known for their ability to generate highly robust spatiotemporal activity patterns in various experimental conditions. These include neuronal avalanches satisfying the…

Adaptation and Self-Organizing Systems · Physics 2022-05-17 I. Y. Tyukin , D. Iudin , F. Iudin , T. Tyukina , V. Kazantsev , I. Mukhina , A. N. Gorban

Computational models of cortical activity provide insight into the mechanisms of higher-order processing in the human brain including planning, perception and the control of movement. Activity in the cortex is ongoing even in the absence of…

Neurons and Cognition · Quantitative Biology 2023-07-07 Lysea Haggie , Thor Besier , Angus McMorland

Several studies have shown that bursting neurons can encode information in the number of spikes per burst: As the stimulus varies, so does the length of individual bursts. The represented stimuli, however, vary substantially among different…

Neurons and Cognition · Quantitative Biology 2013-03-22 Inés Samengo , Germán Mato , Daniel H. Elijah , Susanne Schreiber , Marcelo A. Montemurro

Realizations of low firing rates in neural networks usually require globally balanced distributions among excitatory and inhibitory links, while feasibility of temporal coding is limited by neuronal millisecond precision. We show that…

Neurons and Cognition · Quantitative Biology 2015-06-16 Roni Vardi , Amir Goldental , Hagar Marmari , Haya Brama , Edward Stern , Shira Sardi , Pinhas Sabo , Ido Kanter

Increasing evidence suggests that cortical dynamics during wake exhibits long-range temporal correlations suitable to integrate inputs over extended periods of time to increase the signal-to-noise ratio in decision-making and working memory…

Neurons and Cognition · Quantitative Biology 2017-06-14 Christian Meisel , Andreas Klaus , Vladyslav V. Vyazovskiy , Dietmar Plenz

We study dynamics of a reverberating neural net by means of computer simulation. The net, which is composed of 9 leaky integrate-and-fire (LIF) neurons arranged in a square lattice, is fully connected with interneuronal communication delay…

Neurons and Cognition · Quantitative Biology 2023-06-16 A. Vidybida , O. Shchur

Inhomogeneous temporal processes in natural and social phenomena have been described by bursts that are rapidly occurring events within short time periods alternating with long periods of low activity. In addition to the analysis of…

Physics and Society · Physics 2015-08-26 Hang-Hyun Jo , Juan I. Perotti , Kimmo Kaski , Janos Kertesz

The collective behavior of a network with heterogeneous, resource-limited information processing units (e.g., group of fish, flock of birds, or network of neurons) demonstrates high self-organization and complexity. These emergent…

Machine Learning · Computer Science 2023-10-13 Chenzhong Yin , Mingxi Cheng , Xiongye Xiao , Xinghe Chen , Shahin Nazarian , Andrei Irimia , Paul Bogdan

There is consensus in the current literature that stable states of asynchronous irregular spiking activity require (i) large networks of 10 000 or more neurons and (ii) external background activity or pacemaker neurons. Yet already in 1963,…

Neurons and Cognition · Quantitative Biology 2013-11-07 Marc-Oliver Gewaltig

Neurons in the primary visual cortex are more or less selective for the orientation of a light bar used for stimulation. A broad distribution of individual grades of orientation selectivity has in fact been reported in all species. A…

Neurons and Cognition · Quantitative Biology 2015-06-19 Sadra Sadeh , Stefan Rotter

The brain of mammals are divided into different cortical areas that are anatomically connected forming larger networks which perform cognitive tasks. The cat cerebral cortex is composed of 65 areas organised into the visual, auditory,…

Neurons and Cognition · Quantitative Biology 2015-03-10 Ewandson L. Lameu , Fernando S. Borges , Rafael R. Borges , Antonio M. Batista , Murilo S. Baptista , Ricardo L. Viana