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Recent progress in experimental techniques has enabled us to quantitatively study stochastic and flexible behavior of biological systems. For example, gene regulatory networks perform stochastic information processing and their…

Statistical Mechanics · Physics 2018-06-21 Shun Otsubo , Takahiro Sagawa

Standard Random Boolean Networks display an order-disorder phase transition. We add to the standard Random Boolean Networks a disconnection rule which couples the control and order parameters. By this way, the system is driven to the…

Disordered Systems and Neural Networks · Physics 2009-11-07 Bartolo Luque , Fernando J. Ballesteros , Enrique M. Muro

Random Boolean networks (RBNs) are models of genetic regulatory networks. It is useful to describe RBNs as self-organizing systems to study how changes in the nodes and connections affect the global network dynamics. This article reviews…

Adaptation and Self-Organizing Systems · Physics 2010-09-24 Carlos Gershenson

In this paper we study the phase transitions of different types of Random Boolean networks. These differ in their updating scheme: synchronous, semi-synchronous, or asynchronous, and deterministic or non-deterministic. It has been shown…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Carlos Gershenson

In this paper, we propose a mean-field model which attempts to bridge the gap between random Boolean networks and more realistic stochastic modeling of genetic regulatory networks. The main idea of the model is to replace all regulatory…

Quantitative Methods · Quantitative Biology 2009-11-13 M. Andrecut , S. A. Kauffman

The goal of this tutorial is to promote interest in the study of random Boolean networks (RBNs). These can be very interesting models, since one does not have to assume any functionality or particular connectivity of the networks to study…

Adaptation and Self-Organizing Systems · Physics 2009-09-29 Carlos Gershenson

Mutual information is fundamentally important for measuring statistical dependence between variables and for quantifying information transfer by signaling and communication mechanisms. It can, however, be challenging to evaluate for…

Information Theory · Computer Science 2014-07-29 Clive G. Bowsher , Margaritis Voliotis

We address the practical problems of estimating the information relations that characterize large networks. Building on methods developed for analysis of the neural code, we show that reliable estimates of mutual information can be obtained…

Information Theory · Computer Science 2007-07-13 Noam Slonim , Gurinder S. Atwal , Gasper Tkacik , William Bialek

The emergence of nontrivial collective behavior in networks of coupled chaotic maps is investigated by means of a nonlinear mutual prediction method. The resulting prediction error is used to measure the amount of information that a local…

Chaotic Dynamics · Physics 2009-11-07 L. Cisneros , J. Jimenez , M. G. Cosenza , A. Parravano

Information flow provides a natural measure for the causal interaction between dynamical events. This study extends our previous rigorous formalism of componentwise information flow to the bulk information flow between two complex…

Neurons and Cognition · Quantitative Biology 2021-12-30 X. San Liang

Boolean networks (BNs) are widely used to model the qualitative dynamics of biological systems. Besides the logical rules determining the evolution of each component with respect to the state of its regulators, the scheduling of component…

Logic in Computer Science · Computer Science 2019-06-03 Thomas Chatain , Stefan Haar , Juraj Kolčák , Loïc Paulevé , Aalok Thakkar

We consider a model for heterogeneous 'gene regulatory networks' that is a generalization of the model proposed by Chatterjee and Durrett (2011) as an "annealed approximation" of Kauffmann's (1969) random Boolean networks. In this model,…

Probability · Mathematics 2013-10-17 Shirshendu Chatterjee

The ability of information processing in biologically motivated Boolean networks is of interest in recent information theoretic research. One measure to quantify this ability is the well known mutual information. Using Fourier analysis we…

Information Theory · Computer Science 2012-11-06 Johannes Georg Klotz , David Kracht , Martin Bossert , Steffen Schober

The study of the response of complex dynamical social, biological, or technological networks to external perturbations has numerous applications. Random Boolean Networks (RBNs) are commonly used a simple generic model for certain dynamics…

Disordered Systems and Neural Networks · Physics 2009-04-29 Qiming Lu , Christof Teuscher

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biological question. GRNs are frequently modeled as Boolean…

Molecular Networks · Quantitative Biology 2024-01-19 Claus Kadelka , Taras-Michael Butrie , Evan Hilton , Jack Kinseth , Addison Schmidt , Haris Serdarevic

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

Molecular Networks · Quantitative Biology 2023-02-06 Larry Bull

Boolean networks constitute relevant mathematical models to study the behaviours of genetic and signalling networks. These networks define regulatory influences between molecular nodes, each being associated to a Boolean variable and a…

Discrete Mathematics · Computer Science 2025-06-24 José E. R. Cury , Patrícia Tenera Roxo , Vasco Manquinho , Claudine Chaouiya , Pedro T. Monteiro

Random Boolean Network has been used to find out regulation patterns of genes in organism. his approach is very interesting to use in a game such as N Person PD. Here we assume that action is influenced by input in the form of choices of…

Disordered Systems and Neural Networks · Physics 2007-05-23 Hokky Situngkir , Deni Khanafiah

Boolean networks have been proposed as potentially useful models for genetic control. An important aspect of these networks is the stability of their dynamics in response to small perturbations. Previous approaches to stability have assumed…

Molecular Networks · Quantitative Biology 2015-05-13 Andrew Pomerance , Edward Ott , Michelle Girvan , Wolfgang Losert

We explore a few common models on how correlations affect information. The main model considered is the Shannon mutual information $I(S:R_1,\cdots, R_i)$ over distributions with marginals $P_{S,R_i}$ fixed for each $i$, with the analogy in…

Information Theory · Computer Science 2024-05-27 Ching-Peng Huang