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A double-stranded DNA unravels thermally through intermediate denatured bubble segments. Intrinsically, fluctuations ensue at the bubble boundaries from non-equilibrium (NE) energy exchanges with the environment. However, such details gets…

Soft Condensed Matter · Physics 2018-09-21 Keren Jiang , Faheem Khan , Javix Thomas , Arindam Phani , Thomas Thundat

The dynamics of loops at the DNA denaturation transition is studied. A scaling argument is used to evaluate the asymptotic behavior of the autocorrelation function of the state of complementary bases (either open or closed). The long-time…

Statistical Mechanics · Physics 2008-07-03 Amir Bar , Yariv Kafri , David Mukamel

We develop a simple model to study the effects of an applied force on the melting of a double stranded DNA (dsDNA). Using this model, we could study the stretching, unzipping, rupture and slippage like transition in a dsDNA. We show that in…

Soft Condensed Matter · Physics 2015-05-14 Amit Raj Singh , D. Giri , S. Kumar

Microarray-based genotyping is based on the high discrimination capability of oligonucleotide probes. For detection of Single Nucleotide Polymorphisms (SNPs) single-base discrimination is required. We investigate how various…

Biomolecules · Quantitative Biology 2007-05-23 Thomas Naiser , Oliver Ehler , Timo Mai , Wolfgang Michel , Albrecht Ott

Recent theoretical predictions on DNA mechanical separation induced by pulling forces are numerically tested within a model in which self-avoidance for DNA strands is fully taken into account. DNA strands are described by interacting pairs…

Statistical Mechanics · Physics 2009-11-07 Enzo Orlandini , Somendra M. Bhattacharjee , Davide Marenduzzo , Amos Maritan , Flavio Seno

The denaturation of the double helix is a template for fundamental biological functions such as replication and transcription involving the formation of local fluctuational openings. The denaturation transition is studied for heterogeneous…

Biomolecules · Quantitative Biology 2014-06-03 Marco Zoli

Molecular combing is a powerful and simple method for aligning DNA molecules onto a surface. Using this technique combined with fluorescence microscopy, we observed that the length of lambda-DNA molecules was extended to about 1.6 times…

Biomolecules · Quantitative Biology 2009-11-10 Yu-Ying Liu , Peng-Ye Wang , Shuo-Xing Dou , Wei-Chi Wang , Ping Xie , Hua-Wei Yin , Xing-Dong Zhang

In this study, we proposed a temperature model of magnetic nanoparticle relaxation and a phase measurement method under a mixing-frequency excitation field, which can improve the temperature accuracy of magnetic nanothermometry. According…

Systems and Control · Electrical Eng. & Systems 2024-06-19 Silin Guo , Jay Liu , ZhongZhou Du , Wenzhong Liu

Neutralization probabilities are presented for hyperthermal energy Na+ ions scattered from a Cu(001) crystal as a function of surface temperature and scattered velocity. A large enhancement in neutralization is observed as the temperature…

Condensed Matter · Physics 2009-11-07 C. E. Sosolik , J. R. Hampton , A. C. Lavery , B. H. Cooper , J. B. Marston

We present a study showing cooperative behavior of light emitting quantum dots at room temperature, with large increases in radiative decay rates and efficiencies, in the presence of small gold nanoparticles (1.5 - 4 nm radii) in low…

Mesoscale and Nanoscale Physics · Physics 2015-12-24 George J. Vathakkattil , M. Praveena , J. K. Basu , Murugesan Venkatapathi

A promising new method for measuring intramolecular distances in solution uses small-angle X-ray scattering interference between gold nanocrystal labels (Mathew-Fenn et al, Science, 322, 446 (2008)). When applied to double stranded DNA, it…

Biomolecules · Quantitative Biology 2015-05-13 Alexey K. Mazur

Due to the intertwining between electronic nematic and elastic degrees of freedom, lattice defects and structural inhomogeneities commonly found in crystals can have a significant impact on the electronic properties of nematic materials.…

Superconductivity · Physics 2022-12-13 Aritra Lahiri , Avraham Klein , Rafael M. Fernandes

We extend our analysis of holographic meson dissociation in the presence of an intense magnetic field. In addition to the previously known critical temperature above which the mesons melt, we found that for certain magnetic field…

High Energy Physics - Theory · Physics 2020-06-09 Daniel Ávila , Leonardo Patiño

On the basis of shear modulus measurements on a Pt-based glass, we calculated temperature dependence of the defect concentration c using the Interstitialcy theory. This temperature dependence is compared with temperature dependence of the…

Disordered Systems and Neural Networks · Physics 2023-05-29 A. S. Makarov , G. V. Afonin , R. A. Konchakov , J. C. Qiao , A. N. Vasiliev , N. P. Kobelev , V. A. Khonik

Asymmetric metal-dielectric nanostructures are demonstrated superior optical properties arise from the combination of strong enhancement of their near fields and controllable scattering characteristics which originate from plasmonic and…

The dependence of DNA assemblies conductance on relative humidity is investigated theoretically. Following earlier suggestions, we consider the ionic conductivity through the layers of water adsorbed by DNA molecules. The increase in…

Chemical Physics · Physics 2015-05-14 J. M. Leveritt , S. Tesar , C. Dibaya , R. Shrestha , A. L. Burin

In-situ transmission electron microscopy (TEM) studies reveal key insights into the structural and chemical evolution of nanoparticles (NPs) under external stimuli like heating and biasing, which is critical for evaluating their suitability…

Materials Science · Physics 2025-02-10 Abhijit Roy , Simon Hettler , Raul Arenal

The hybridization and dehybridization of DNA subject to tension is relevant to fundamental genetic processes and to the design of DNA-based mechanobiology assays. While strong tension accelerates DNA melting and decelerates DNA annealing,…

Biological Physics · Physics 2022-04-20 Derek J. Hart , Jiyoun Jeong , James C. Gumbart , Harold D. Kim

The cations, in form of salt, present in the solution containing DNA play a crucial role in the opening of two strands of DNA. We use a simple non linear model and investigate the role of these cations on the mechanical unzipping of DNA.…

Soft Condensed Matter · Physics 2014-09-08 Amar Singh , Navin Singh

We study the dynamics of DNA hairpin formation using oxDNA, a nucleotide-level coarse-grained model of DNA. In particular, we explore the effects of the loop stacking interactions and non-native base pairing on the hairpin closing times. We…

Biological Physics · Physics 2014-12-12 Majid Mosayebi , Flavio Romano , Thomas E. Ouldridge , Ard A. Louis , Jonathan P. K. Doye
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