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The emergence of Big Data has enabled new research perspectives in the discrete choice community. While the techniques to estimate Machine Learning models on a massive amount of data are well established, these have not yet been fully…

Optimization and Control · Mathematics 2020-12-23 Gael Lederrey , Virginie Lurkin , Tim Hillel , Michel Bierlaire

Dynamic models have been successfully used in producing estimates of HIV epidemics at national level, due to their epidemiological nature and their ability to simultaneously estimate prevalence, incidence, and mortality rates. Recently, HIV…

Methodology · Statistics 2016-02-19 Le Bao , Ben Sheng , Xiaoyue Niu , Yuan Tang , Tim Brown , Peter D. Ghys , Jeff W. Eaton

In this paper, we propose a computer-oriented method of construction of optimal group sequential hypothesis tests with variable group sizes. In particular, for independent and identically distributed observations we obtain the form of…

Methodology · Statistics 2023-03-30 Andrey Novikov

One important issue commonly encountered in the analysis of microarray data is to decide which and how many genes should be selected for further studies. For discriminant microarray data analyses based on statistical models, such as the…

Quantitative Methods · Quantitative Biology 2009-11-09 Wentian Li , Fengzhu Sun , Ivo Grosse

Motivation: In predicting HIV therapy outcomes, a critical clinical question is whether using historical information can enhance predictive capabilities compared with current or latest available data analysis. This study analyses whether…

Existing strategies for determining the optimal treatment or monitoring strategy typically assume unlimited access to resources. However, when a health system has resource constraints, such as limited funds, access to medication, or…

Applications · Statistics 2019-03-18 Ellen C Caniglia , Eleanor J Murray , Miguel A Hernan , Zach Shahn

The paper considers a time-adaptive method for determination of drug efficacy in a parameter identification problem (PIP) for system of ordinary differential equations (ODE) which describe dynamics of the primary HIV infection. Optimization…

Numerical Analysis · Mathematics 2020-08-26 L. Beilina , I. Gainova

Many techniques for handling missing data have been proposed in the literature. Most of these techniques are overly complex. This paper explores an imputation technique based on rough set computations. In this paper, characteristic…

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Fulufhelo Vincent Nelwamondo , Tshilidzi Marwala

Thin-film solar cells are predominately designed similar to a stacked structure. Optimizing the layer thicknesses in this stack structure is crucial to extract the best efficiency of the solar cell. The commonplace method used in…

Neural and Evolutionary Computing · Computer Science 2020-04-08 Premkumar Vincent , Gwenaelle Cunha Sergio , Jaewon Jang , In Man Kang , Jaehoon Park , Hyeok Kim , Minho Lee , Jin-Hyuk Bae

Incidence estimation of HIV infection can be performed using recent infection testing algorithm (RITA) results from a cross-sectional sample. This allows practitioners to understand population trends in the HIV epidemic without having to…

Methodology · Statistics 2023-09-13 Marlena Bannick , Deborah Donnell , Richard Hayes , Oliver Laeyendecker , Fei Gao

In real-time trajectory planning for unmanned vehicles, on-board sensors, radars and other instruments are used to collect information on possible obstacles to be avoided and pathways to be followed. Since, in practice, observations of the…

Methodology · Statistics 2013-09-25 Adriano Zanin Zambom , Julian A. A. Collazos , Ronaldo Dias

In general, we can not use algebraic or enumerative methods to optimize a quality control (QC) procedure so as to detect the critical random and systematic analytical errors with stated probabilities, while the probability for false…

Neural and Evolutionary Computing · Computer Science 2018-12-03 Aristides T. Hatjimihail , Theophanes T. Hatjimihail

Randomized benchmarking (RB) is a widely used method for estimating the average fidelity of gates implemented on a quantum computing device. The stochastic error of the average gate fidelity estimated by RB depends on the sampling strategy…

Quantum Physics · Physics 2021-09-17 Toshinari Itoko , Rudy Raymond

Longitudinal cohorts to determine the incidence of HIV infection are logistically challenging, so researchers have sought alternative strategies. Recency test methods use biomarker profiles of HIV-infected subjects in a cross-sectional…

Methodology · Statistics 2022-01-13 Fei Gao , Marlena S. Bannick

The analysis of the leukemia data from Whitehead/MIT group is a discriminant analysis (also called a supervised learning). Among thousands of genes whose expression levels are measured, not all are needed for discriminant analysis: a gene…

Biological Physics · Physics 2007-05-23 Wentian Li , Yaning Yang

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Methodology · Statistics 2022-03-04 Kiheiji Nishida

In this paper we study a family of variance reduction methods with randomized batch size---at each step, the algorithm first randomly chooses the batch size and then selects a batch of samples to conduct a variance-reduced stochastic…

Machine Learning · Computer Science 2018-08-08 Xuanqing Liu , Cho-Jui Hsieh

Given a collection of features available for inclusion in a predictive model, it may be of interest to quantify the relative importance of a subset of features for the prediction task at hand. For example, in HIV vaccine trials, participant…

Methodology · Statistics 2025-03-27 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

The graph partitioning problem (GPP) is among the most challenging models in optimization. Because of its NP-hardness, the researchers directed their interest towards approximate methods such as the genetic algorithms (GA). The edge-based…

Neural and Evolutionary Computing · Computer Science 2023-07-21 Ali Chaouche , Menouar Boulif

Gene expression data is widely used in disease analysis and cancer diagnosis. However, since gene expression data could contain thousands of genes simultaneously, successful microarray classification is rather difficult. Feature selection…

Machine Learning · Computer Science 2016-12-28 Li-Yeh Chuang , Chao-Hsuan Ke , Cheng-Hong Yang