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Although the interest in the the use of social and information networks has grown, most inferences on networks assume the data collected represents the complete. However, when ignoring missing data, even when missing completely at random,…

Methodology · Statistics 2022-03-25 Tyler Vu , Tuo Lin , Jingjing Zou , Vladimir Novitsky , Xin Tu , Victor De Gruttola

Predicting the cheapest sample size for the optimal stratification in multivariate survey design is a problem in cases where the population frame is large. A solution exists that iteratively searches for the minimum sample size necessary to…

Methodology · Statistics 2018-06-18 Mervyn O'Luing , Steven Prestwich , S. Armagan Tarim

Cross-sectional HIV incidence estimation leverages recency test results to determine the HIV incidence of a population of interest, where recency test uses biomarker profiles to infer whether an HIV-positive individual was "recently"…

Methodology · Statistics 2023-11-21 Qi Wang , Ann Duerr , Fei Gao

Optimization problems frequently appear in any scientific domain. Most of the times, the corresponding decision problem turns out to be NP-hard, and in these cases genetic algorithms are often used to obtain approximated solutions. However,…

Neural and Evolutionary Computing · Computer Science 2024-02-02 Alba Muñoz , Fernando Rubio

We introduce genetic algorithms as a means to estimate the accuracy required to discriminate among different models using experimental observables. We exemplify the technique in the context of the minimal supersymmetric standard model. If…

High Energy Physics - Phenomenology · Physics 2009-11-10 B. C. Allanach , D. Grellscheid , F. Quevedo

One of the key difficulties in using estimation-of-distribution algorithms is choosing the population size(s) appropriately: Too small values lead to genetic drift, which can cause enormous difficulties. In the regime with no genetic drift,…

Neural and Evolutionary Computing · Computer Science 2023-09-11 Benjamin Doerr , Weijie Zheng

The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scanning techniques have been recently proposed to…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

The problem of fast items retrieval from a fixed collection is often encountered in most computer science areas, from operating system components to databases and user interfaces. We present an approach based on hash tables that focuses on…

Neural and Evolutionary Computing · Computer Science 2020-07-17 Dan Domnita , Ciprian Oprisa

Motivation: HIV is difficult to treat because its virus mutates at a high rate and mutated viruses easily develop resistance to existing drugs. If the relationships between mutations and drug resistances can be determined from historical…

Quantitative Methods · Quantitative Biology 2019-07-08 Li Xing , Mary Lesperance , Xuekui Zhang

High-throughput shotgun sequence data makes it possible in principle to accurately estimate population genetic parameters without confounding by SNP ascertainment bias. One such statistic of interest is the proportion of heterozygous sites…

Populations and Evolution · Quantitative Biology 2012-12-18 Katarzyna Bryc , Nick Patterson , David Reich

HIV epidemiological data is increasingly complex, requiring advanced computation for accurate cluster detection and forecasting. We employed quantum-accelerated machine learning to analyze HIV prevalence at the ZIP-code level using AIDSVu…

Machine Learning · Computer Science 2025-07-02 Don Roosan , Saif Nirzhor , Rubayat Khan , Fahmida Hai , Mohammad Rifat Haidar

Microarray cancer gene expression data comprise of very high dimensions. Reducing the dimensions helps in improving the overall analysis and classification performance. We propose two hybrid techniques, Biogeography - based Optimization -…

Neural and Evolutionary Computing · Computer Science 2016-11-18 Sarvesh Nikumbh , Shameek Ghosh , Valadi Jayaraman

This thesis investigates the use of problem-specific knowledge to enhance a genetic algorithm approach to multiple-choice optimisation problems.It shows that such information can significantly enhance performance, but that the choice of…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

Covariate adjustment is an approach to improve the precision of trial analyses by adjusting for baseline variables that are prognostic of the primary endpoint. Motivated by the SEARCH Universal HIV Test-and-Treat Trial (2013-2017), we tell…

Methodology · Statistics 2025-12-16 Laura B. Balzer , Mark J. van der Laan , Maya L. Petersen

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

Choosing an optimal strategy for hierarchical group testing is an important problem for practitioners who are interested in disease screening with limited resources. For example, when screening for infectious diseases in large populations,…

Methodology · Statistics 2020-02-27 Yaakov Malinovsky , Gregory Haber , Paul S. Albert

Microbiota profiles measure the structure of microbial communities in a defined environment (known as microbiomes). In the past decade, microbiome research has focused on health applications as a result of which the gut microbiome has been…

Quantitative Methods · Quantitative Biology 2021-05-11 Benjamin Wingfield , Sonya Coleman , T. M. McGinnity , Anthony J. Bjourson

HIV/AIDs Regimen specification one of many problems for which bioinformaticians have implemented and trained machine learning methods such as neural networks. Predicting HIV resistance would be much easier, but unfortunately we rarely have…

Computers and Society · Computer Science 2009-12-22 P. Balasubramanie , M. Lilly Florence

The Sustainable Development Goals (SDGs) of the United Nations provide a blueprint of a better future by 'leaving no one behind', and, to achieve the SDGs by 2030, poor countries require immense volumes of development aid. In this paper, we…

Machine Learning · Statistics 2024-06-18 Milan Kuzmanovic , Dennis Frauen , Tobias Hatt , Stefan Feuerriegel

Fine resolution estimates of demographic and socioeconomic attributes are crucial for planning and policy development. While several efforts have been made to produce fine-scale gridded population estimates, socioeconomic features are…