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Biomembranes are thin capacitors with the unique feature of displaying phase transitions in a physiologically relevant regime. We investigate the voltage and lateral pressure dependence of their capacitance close to their chain melting…

Biological Physics · Physics 2012-09-18 Thomas Heimburg

Though membrane trafficking of cell junction proteins has been studied extensively for more than two decades, the accumulated knowledge remains fragmentary. The goal of this review is to synthesize published studies on the membrane…

Subcellular Processes · Quantitative Biology 2021-04-13 Arie Horowitz

Schizophrenia (SZ) is a brain disorder leading to detached mind's normally integrated processes. Hence, the exploration of the symptoms in relation to functional connectivity (FC) had great relevance in the field. FC can be investigated on…

Neurons and Cognition · Quantitative Biology 2026-04-08 Davide Coluzzi , Giuseppe Baselli

Biological membranes are fundamental components of living organisms that play an undeniable role in their survival. Molecular dynamics (MD) serves as an essential computational tool for studying biomembranes on molecular and atomistic…

Soft Condensed Matter · Physics 2025-09-15 Emad Pirhadi , Juan M. Vanegas , Mithila Farin , Jeffrey W. Schertzer , Xin Yong

Single cell and regularly cells docking inside the microstructure of microfluidic systems are advantageous in different analyses of single cells exposed to equal drug concentration and mechanical stimulus. In this study, we investigated…

Biological Physics · Physics 2020-08-05 Sina Ahandoust , Maryam Saadatmand

The rigorous analysis of textbook result(Chiu and Quinn, 1974) gives unexpectedly the dramatic change of magnetoplasmon spectrum taking into account both the arbitrary dissipation and asymmetric off-plane structure of 2D system. For given…

Mesoscale and Nanoscale Physics · Physics 2017-09-21 M. V. Cheremisin

Two-dimensional (2D) mechanical models of confluent tissues have related the mechanical state of a monolayer of cells to the average perimeter length of the cell cross sections, predicting floppiness or rigidity of the material. For the…

Soft Condensed Matter · Physics 2025-01-30 Jairo M. Rojas , Mayisha Z. Nakib , Vivian W. Tang , William M. Brieher , Sascha Hilgenfeldt

Subdiffusion is a hallmark of complex systems, ranging from protein folding to transport in viscoelastic media. However, despite its pervasiveness, the mechanistic origins of subdiffusion remain contested. Here, we analyze both Markovian…

Soft Condensed Matter · Physics 2025-06-04 Anton Klimek , Benjamin A. Dalton , Roland R. Netz

Suspensions of Active Brownian Particles (ABP) undergo motility induced phase separation (MIPS) over a wide range of mean density and activity strength [1], even in the absence of an explicit attraction. Negative values of the mechanical…

Soft Condensed Matter · Physics 2022-02-07 Enrique Chacon , Francisco Alarcon , Jorge Ramirez , Pedro Tarazona , Chantal Valeriani

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

Transforming growth factor beta (TGF$\beta$) plays a central role in morphogenesis, growth, and cell differentiation. This cytokine is particularly important in cartilage where it regulates cell proliferation and extracellular matrix…

Tissues and Organs · Quantitative Biology 2015-05-27 Catherine Baugé , Olivier Cauvard , Sylvain Leclercq , Philippe Galéra , Karim Boumédiene

Using computational and theoretical approaches, we investigate the snap-through transition of buckled graphene membranes. Our main interest is related to the possibility of using the buckled membrane as a plate of capacitor with memory…

Mesoscale and Nanoscale Physics · Physics 2018-04-26 R. D. Yamaletdinov , O. V. Ivakhnenko , O. V. Sedelnikova , S. N. Shevchenko , Y. V. Pershin

Muscle uses Ca2+ as a messenger to control contraction and relies on ATP to maintain the intracellular Ca2+ homeostasis. Mitochondria are the major sub-cellular organelle of ATP production. With a negative inner membrane potential,…

Biomolecules · Quantitative Biology 2016-07-29 Jingsong Zhou , Kamal Dhakal , Jianxun Yi

Morphogenesis is the process whereby the body of an organism develops its target shape. The morphogen BMP is known to play a conserved role across bilaterian organisms in determining the dorsoventral (DV) axis. Yet, how BMP governs the…

A significant association between a polymorphism in the D repeat of the gene encoding asporin and osteoarthritis, the most frequent of articular diseases, has been recently reported. The goal of the present study was to investigate the…

Tissues and Organs · Quantitative Biology 2015-05-27 Elise Duval , Nicolas Bigot , Magalie Hervieu , Ikuyo Kou , Sylvain Leclercq , Philippe Galéra , Karim Boumediene , Catherine Baugé

We are interested to explore the limit in using deep learning (DL) to study the electromagnetic response for complex and random metasurfaces, without any specific applications in mind. For simplicity, we focus on a simple pure reflection…

Signal Processing · Electrical Eng. & Systems 2024-06-19 Tianning Zhang , Chun Yun Kee , Yee Sin Ang , L. K. Ang

The perpendicular magnetic anisotropy (PMA) arising at the interface between ferromagnetic transition metals and metallic oxides are investigated via first-principles calculations. In this work very large values of PMA up to 3 erg/cm$^2$ at…

Materials Science · Physics 2011-10-13 H. X. Yang , J. H. Lee , M. Chshiev , A. Manchon , K. H. Shin , B. Dieny

The electrostatic interactions of phosphate groups and counter ions critically affect the structure, function and reactivity of DNA or RNA. We present a joint experimental-theoretical investigation of dimethyl phosphate (DMP-) in aqueous…

Bulk single-crystal relaxor-ferroelectrics, like Pb(Mg1/3Nb2/3)O3-PbTiO3 (PMN-PT), are widely known for their large piezoelectricity. This is attributed to polarization rotation which is facilitated by the presence of various crystal…

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo