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Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

In this paper we investigate the possibility to detect the hypothesized liquid-liquid critical point of water in supercooled aqueous solutions of salts. Molecular dynamics computer simulations are conducted on bulk TIP4P water and on an…

Soft Condensed Matter · Physics 2010-04-08 D. Corradini , M. Rovere , P. Gallo

Microfluidic devices have been the subject of considerable attention in recent years. The development of novel microfluidic devices, their evaluation, and their validation requires simulations. While common methods based on Computational…

Fluid Dynamics · Physics 2024-11-05 Maria Emmerich , Florina Costamoling , Robert Wille

We use pervaporation-based microfluidic devices to concentrate species in aqueous solutions with spatial and temporal control of the process. Using experiments and modelling, we quantitatively describe the advection-diffusion behavior of…

Soft Condensed Matter · Physics 2009-11-11 Jacques Leng , Barbara Lonetti , Patrick Tabeling , Mathieu Joanicot , Armand Ajdari

Droplets, sub-millilitre liquid volumes with at least one interface, have traditionally served as compartments for storing, transporting, and delivering materials. Beyond familiar applications in food, coatings, and consumer goods, they…

Soft Condensed Matter · Physics 2025-12-16 Joe Forth , Robert Malinowski , Giorgio Volpe

Much of our knowledge about dynamics and functionality of molecular systems has been achieved with femtosecond time-resolved spectroscopy. Despite extensive technical developments over the past decades, some classes of systems have eluded…

Chemical Physics · Physics 2020-03-25 Bernhard Thaler , Miriam Meyer , Pascal Heim , Markus Koch

We reveal an unreported physical mechanism that enables the pre-concentration, sorting and characterization of charged polystyrene nanobeads and liposomes dispersed in a continuous flow within a straight micron-sized channel. Initially, a…

In this work, we present two types of microfluidic chips involving magnetic nanoparticles dispersed in cyclohexane with oleic acid. In the first case, the hydrophobically coated nanoparticles are self-assembled with an amphiphilic diblock…

Flow-based microfluidic biochips are widely used in lab- on-a-chip experiments. In these chips, devices such as mixers and detectors connected by micro-channels execute specific operations. Intermediate fluid samples are saved in storage…

Emerging Technologies · Computer Science 2017-05-16 Tsun-Ming Tseng , Bing Li , Tsung-Yi Ho , Ulf Schlichtmann

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate…

Soft Condensed Matter · Physics 2015-02-16 Sukumar Rajauria , Christopher Axline , Claudia Gottstein , Andrew N. Cleland

We propose a numerical approach to study the mechanics of a flowing bubble in a constraint micro channel. Using an open source two phase flow solver (Gerris, gfs.sourceforge.net) we compute solutions of the bubble dynamics (i.e. shape and…

Fluid Dynamics · Physics 2015-07-16 Jose-Maria Fullana , Yue Ling , Stéphane Popinet , Christophe Josserand

The fast evaporative cooling of micrometer-sized water droplets in vacuum offers the appealing possibility to investigate supercooled water - below the melting point but still a liquid - at temperatures far beyond the state-of-the-art.…

In this work, we used a coupled level set and volume of fluid (CLSVOF) computational method for studying the generation of microdroplets in a two dimensional circular co-flow microfluidic device. The fundamental understanding of shear…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

Tracking the evolution of an individual nanodroplet of liquid in real-time remains an outstanding challenge. Here a miniature optomechanical resonator detects a single nanodroplet landing on a surface and measures its subsequent evaporation…

Fluid Dynamics · Physics 2022-11-23 Samantha Sbarra , Louis Waquier , Stephan Suffit , Aristide Lemaître , Ivan Favero

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…

Fast and programmable transport of liquid droplets on a solid substrate is desirable in microfluidic, thermal, biomedical, and energy devices. Past research has focused on designing substrates with asymmetric structures or gradient…

Liquid dispensing and writing in the extremely small size regime are important for applications in many current technologies, such as micro/nano fabrication, biological/chemical patterning and analysis, and drug discovery. Most of current…

Soft Condensed Matter · Physics 2016-03-14 Hualai Dong , Xing Yang , Cunjing Lv , Quanshui Zheng

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

Solubility and interfacial energy are two fundamental parameters underlying the competitive nucleation of polymorphs. However, solubility measurement of metastable phases comes with a risk of solventmediated transformations which can render…

Materials Science · Physics 2023-09-15 Ruel Cedeno , Romain Grossier , Nadine Candoni , Stéphane Veesler

Preconcentration of the target compound is a critical step that ensures the accuracy of the subsequent chemical analysis. In this work, we present a straightforward yet effective liquid-liquid extraction approach based on surface…

Chemical Physics · Physics 2023-06-27 Hongyan Wu , Quynh Nhu Le , Binglin Zeng , Xuehua Zhang