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Aerobreakup of fluid droplets under the influence of impulsively generated high-speed gas flow using an open-ended shock tube is studied using experiments and numerical simulations. Breakup of mm-sized droplets at high Weber number was…

Fluid Dynamics · Physics 2022-06-24 James Leung , Mohana Gurunadhan , Shyam Menon

In the recent years, there has been a growing interest in droplet-based (digital) microfluidics for which, reliable means of droplet manipulation are required. In this study we demonstrate thermal actuation of droplets on liquid platforms,…

Fluid Dynamics · Physics 2010-10-19 Ehsan Yakhshi-Tafti , Hyoung J. Cho , Ranganathan Kumar

Cleaner analytic technique for quantifying compounds in dense suspension is needed for wastewater and environment analysis, chemical or bio-conversion process monitoring, biomedical diagnostics, food quality control among others. In this…

Soft Condensed Matter · Physics 2021-05-11 Jae Bem You , Detlef Lohse , Xuehua Zhang

We report on experiments that consist in deforming a collection of monodisperse droplets produced by a microfluidic chip through a flow-focusing device. We show that a proper numerical modelling of the flow is necessary to access the stress…

Soft Condensed Matter · Physics 2018-05-23 Corentin Trégouët , Thomas Salez , Cécile Monteux , Mathilde Reyssat

Solvent shifting is a process in which a non-solvent is added to a solvent/solute mixture and extracts the solvent. The solvent and the non-solvent are miscible. Because of solution supersaturation a portion of the solute transforms to…

Fluid Dynamics · Physics 2014-09-30 Ramin Hajian , Steffen Hardt

In this paper we present a comprehensive study of the step-emulsification process for high-throughput production of (sub-)$\mu$m-size monodisperse droplets. The microfluidic device combines a Hele-Shaw nanofluidic cell with a step-like…

Fluid Dynamics · Physics 2014-05-15 Z. Li , A. M. Leshansky , L. M. Pismen , P. Tabeling

High throughput screening of small molecules and natural products is costly, requiring significant amounts of time, reagents, and operating space. Although microarrays have proven effective in the miniaturization of screening for certain…

Biomolecules · Quantitative Biology 2022-10-17 Tracey N. Bell , Aubrey E. Kusi-Appiaha , Pengfei Lyu , L. Zhu , F. Zhu , David Van Winkle , Hongyuan Cao , M. Singh , Steven Lenhert

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

Uncovering the heterogeneity of cell populations is a long-standing goal in fields ranging from antimicrobial resistance to cancer research. Emerging technology platforms such as droplet microfluidics hold the promise to decipher cellular…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Vasileios Anagnostidis , Benjamin Sherlock , Jeremy Metz , Philip Mair , Florian Hollfelder , Fabrice Gielen

The investigation of liquid flow at the nanoscale is a key area of applied research with high relevance to Physics, Chemistry and Biology. We introduce a method and a device that allows to spatially resolve liquid flow by integrating an…

Mesoscale and Nanoscale Physics · Physics 2016-08-24 R. F. Neumann , M. Engel , M. Steiner

Making liquid droplets move spontaneously on solid surfaces is a key challenge in lab-on-chip and heat exchanger technologies. The best-known mechanism, a wettability gradient, does not generally move droplets rapidly enough and cannot…

Soft Condensed Matter · Physics 2015-03-13 Cunjing Lv , Chao Chen , Yin-Chuan Chuang , Fan-Gang Tseng , Yajun Yin , Francois Grey , Quanshui Zheng

We have developed a microfluidic tool to measure the diffusion coefficient $D$ of solutes in an aqueous solution, by following the temporal relaxation of an initially steep concentration gradient in a microchannel. Our chip exploits…

Soft Condensed Matter · Physics 2022-08-23 Hoang-Thanh Nguyen , Anne Bouchaudy , Jean-Baptiste Salmon

Block copolymers often create droplets when placed on a substrate. Such nanostructured droplets can be arranged into regular microstructured arrays, thereby forming hierarchically organized materials that can be used in microelectronics,…

Soft Condensed Matter · Physics 2026-05-04 Artem Petrov , Guillermo A. Hernández-Mendoza , Alfredo Alexander-Katz

Ensemble averaging experiments may conceal many fundamental molecular interactions. To overcome that, a high-throughput detection of single molecules or colloidal nanodots is crucial for biomedical, nanoelectronic, and solid-state…

Biological Physics · Physics 2019-07-15 Siddharth Ghosh , Narain Karedla , Ingo Gregor

Accelerating material discovery has tremendous societal and industrial impact, particularly for pharmaceuticals and clean energy production. Many experimental instruments have some degree of automation, facilitating continuous running and…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Gabriella Pizzuto , Jacopo de Berardinis , Louis Longley , Hatem Fakhruldeen , Andrew I. Cooper

Scalable technologies for the production of bio-compatible complex microfibers with controllable size and composition at competitively high throughput are urgently needed in order to meet the growing demand for such microstructures in…

Applied Physics · Physics 2022-08-11 Marangon Francesco , Baumgartner David , Planchette Carole

We investigate the behaviour of a binary surfactant solution (AOT/water) as it is progressively concentrated in microfluidic evaporators. We observe in time a succession of phase transitions from a dilute solution up to a dense state, which…

Soft Condensed Matter · Physics 2007-05-23 Jacques Leng , Mathieu Joanicot , Armand Ajdari

Reliable measurement of droplet/bubble size and velocity distributions in dense flows is desired in a variety of research fields, both for laboratory and industrial use. A new type of single-mode monofiber optical probe manufactured by A2…

Applied Physics · Physics 2021-10-26 Mathieu Alonzo , Anthony Lefebvre , Zhujun Huang , Stéphane Gluck , Alain Cartellier

Droplets are natural candidates for use as microfluidic reactors, if active control of their formation and transport can be achieved. We show here that localized heating from a laser can block the motion of a water-oil interface, acting as…

Fluid Dynamics · Physics 2015-06-26 C. N. Baroud , J. -P. Delville , F. Gallaire , R. Wunenburger

The analysis of nano-and microparticle suspensions with micro systems affords improved space-time yields, selectivity, reaction residence times and conversions capabilities. These capabilities are of primary importance in various fields of…

Instrumentation and Detectors · Physics 2022-01-24 F. Onofri , Isaac Rodríguez-Ruiz , Fabrice Lamadie , Fabrice Onofri