Other Quantitative Biology
This article examines the advantages and disadvantages of Large Language Models (LLMs) and Artificial Intelligence (AI) in research and education and proposes the urgent need for an international statement to guide their responsible use.…
The results of applying neural replicator analysis (NRA) to the genomes of viruses belonging to the genus Flavivirus are presented. It is shown that the viral genomes considered in this study can be placed in five different cells of the…
We provide a critique of mathematical biology in light of rapid developments in modern machine learning. We argue that out of the three modelling activities -- (1) formulating models; (2) analysing models; and (3) fitting or comparing…
Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be…
Rhodopsin is a G-protein coupled receptor found in retinal rod cells, where it mediates monocrhromatic vision in dim light. It is one of the most studied proteins with thousands of reviewed entries in Uniprot. It has seven transmembrane…
Africa is experiencing extensive biodiversity loss due to rapid changes in the environment, where natural resources constitute the main instrument for socioeconomic development and a mainstay source of livelihoods for an increasing…
The Garo Hills have always been fascination to the naked human eyes. The hills are the shelter of the earliest human habitation of Bangladesh. It is a place of ancient cultures and many botanical wonders. It is situated in the most northern…
Due to the high mutation rate of the virus, the COVID-19 pandemic evolved rapidly. Certain variants of the virus, such as Delta and Omicron, emerged with altered viral properties leading to severe transmission and death rates. These…
Harvesting organic matter from wastewater is widely applied to maximize energy recovery; however, it limits the applicability of secondary treatment for acceptable effluent discharge into surface water bodies. To turn this bottleneck issue…
Deconvolution of cell mixtures in "bulk" transcriptomic samples from homogenate human tissue is important for understanding the pathologies of diseases. However, several experimental and computational challenges remain in developing and…
Over the past 150 years, vaccines have revolutionized the relationship between people and disease. During the COVID-19 pandemic, technologies such as mRNA vaccines have received attention due to their novelty and successes. However, more…
COVID-19 has quickly spread across the globe, becoming a pandemic. This disease has a variable impact in different countries depending on their cultural norms, mitigation efforts and health infrastructure. In India, a majority of people…
Like other types of computational research, modeling and simulation of biological processes (biomodels) is still largely communicated without sufficient detail to allow independent reproduction of results. But reproducibility in this area…
Agricultural fertilizers are essential to enhance proper growth and crop yield. Chemical fertilizers endanger ecosystems, soil, plants, and animal and human lives. This has increased interest in biofertilizers which are products that…
The estimand framework included in the addendum to the ICH E9 guideline facilitates discussions to ensure alignment between the key question of interest, the analysis, and interpretation. Therapeutic knowledge and drug mechanism play a…
COVID-19 outbreak has rapidly evolved into a global pandemic. The impact of COVID-19 on patient journeys in oncology represents a new risk to interpretation of trial results and its broad applicability for future clinical practice. We…
This article is a reproduction of a Fraunhofer ITWM report from 28 June 2021 on the contribution of various non-pharmaceutical measures in breaking the 3rd Corona wave in Germany. The main finding is that testing contributed more to the…
Silver nanoparticles (AgNP's) possess inherent biological potentials that have obliged an alternative, eco-friendly, sustainable approach to "Green Synthesis." In the present study, we synthesized Green Silver Nanoparticles (GAgNP's) using…
This study explores the emergence of life through a simulation model approach. The model "Multi-set chemical lattice model" is a model that allows virtual molecules of multiple types to be placed in each lattice cell on a two-dimensional…
The rise of advanced chatbots, such as ChatGPT, has sparked curiosity in the scientific community. ChatGPT is a general-purpose chatbot powered by large language models (LLMs) GPT-3.5 and GPT-4, with the potential to impact numerous fields,…