Other Quantitative Biology
With increased access to data and the advent of computers, the use of statistical tools and numerical simulations is becoming commonplace for ecologists. These approaches help improve our understanding of ecological phenomena and their…
The ac4C modification on mRNA has been demonstrated to be associated with various diseases; however, its molecular mechanism remains unclear. The wet lab experiments produced relatively rough data, which lack precise ac4C modification…
We discuss in this article the creation and organization of a national core facility for bioimage analysis, based on a distributed team. F-BIAS federates bioimage analysts across France and relies on them to deliver services to the…
To double the cellular population of ribosomes, a fraction of the active ribosomes is allocated to synthesize ribosomal proteins. Subsequently, these ribosomal proteins enter the ribosome self-assembly process, synthesizing new ribosomes…
This study utilizes mathematical models to assess progress toward achieving the UNAIDS 90-90-90 and 95-95-95 targets aimed at managing and eradicating HIV/AIDS. It contrasts stochastic and deterministic models, focusing on their utility in…
The ULEX model, in its present state, involves the study of the biomass and the population of the shrub Ulex parviflorus Pourret, but while being a dynamic model, it is static in the sense that it does not imply the appearance of new…
Chronotypes allow for comparisons of one individual's daily rhythms to that of others and the environment. Mismatch between an individual's chronotype and the timing constraints of their social environment create social jet lag, which is…
Accurate 3D modelling of grapevines is crucial for precision viticulture, particularly for informed pruning decisions and automated management techniques. However, the intricate structure of grapevines poses significant challenges for…
Tight regulation of messenger RNA (mRNA) stability is essential to ensure accurate gene expression in response to developmental and environmental cues. mRNA stability is controlled by mRNA decay pathways, which have traditionally been…
Artificial intelligence (AI) is transforming scientific research, including proteomics. Advances in mass spectrometry (MS)-based proteomics data quality, diversity, and scale, combined with groundbreaking AI techniques, are unlocking new…
Guidelines for managing scientific data have been established under the FAIR principles requiring that data be Findable, Accessible, Interoperable, and Reusable. In many scientific disciplines, especially computational biology, both data…
Background: Literature shows that most of the information on the toxicity of gluten is generated from survey and observational studies, resulting in inconsistent outcomes and a decrease in the acceptability of gluten-rich foods. To…
Objective - This work introduces Dareplane, a modular and broad technology-agnostic open source software platform for brain-computer interface research with an application focus on adaptive deep brain stimulation (aDBS). One difficulty for…
Sharing diverse genomic and other biomedical datasets is critical to advance scientific discoveries and their equitable translation to improve human health. However, data sharing remains challenging in the context of legacy datasets,…
This study presents a theoretical model for a self-replicating mechanical system inspired by biological processes within living cells and supported by computer simulations. The model decomposes self-replication into core components, each of…
This study employed neutral PBS buffer combined with ammonium sulfate fractionation to isolate peptide-active fractions (PD-30, PD-50, PD-80) from Cuminum cyminum L.seeds (cumin) and systematically evaluated their antimicrobial,…
Laboratory research is a complex, collaborative process that involves several stages, including hypothesis formulation, experimental design, data generation and analysis, and manuscript writing. Although reproducibility and data sharing are…
As the next step in extraterrestrial exploration, many engineers and scientists around the country revealed their intense interest to enable multiplanetary human life, including colonizing Mars. This study proposes that architecture on Mars…
Cuminum cyminum L. (cumin) is a medicinal and edible plant widely used in traditional Chinese medicine (TCM) for treating various ailments, including diarrhea, abdominal pain, inflammation, asthma, and diabetes. While previous research has…
Previously, we reported on a new meta-registry for NAR published databases focusing on high-quality annotations regarding database availability and longevity. With over two years of continued manual curation, here, we report on recent…