Biological Physics
Cells control their size to cope with noise during growth and division. Eukaryotic cells exhibiting "sizer" control (targeting a specific size before dividing) may rely on molecular concentration thresholds, but simple implementations of…
We investigate delay-induced collective dynamics in a two-layer multiplex FitzHugh Nagumo network with nonlocal intra layer coupling and delayed inter layer interactions. While delay effects are often treated as secondary, we show that…
In this work, we characterized the material properties of an animal model of the rotator cuff tendon using full volume datasets of both its intact and injured states by capturing internal strain behavior throughout the tendon. Our…
Neuromechanics aims to understand the link between an animal's neural activity and its physical behaviors. Recent advances in experimental and machine learning techniques enable simultaneous recordings of neural and locomotion dynamics over…
In proliferating cell populations, adaptive changes to biochemical reactions can change a cell's division time, which in turn can change the population size. However, biochemical reactions are subject to noise, and therefore the conditions…
Peptide nanofibrils (PNFs) and peptide amphiphiles (PAs) are promising tools for enhancing viral transduction and gene transfer. However, quantitative insight into how their supramolecular architecture governs virion-cell interactions is…
The burst approximation is a widely used technique to simplify stochastic gene expression models. However, the dynamics and analytical properties of the protein number distribution in gene expression models under the burst approximation are…
Lumens are cavities enclosed by polarized cells that are essential for organ function, from nutrient transport in the gut to gas exchange in the lungs. Defects in lumen formation are associated with severe diseases, including polycystic…
Optical imaging technologies are central to discovery in the life and physical sciences, yet their impact depends on how readily they can be built, adapted, and sustained across laboratories. Digital fabrication, including desktop 3D…
The SARS-CoV-2 RNA pseudoknot is a promising target for antiviral intervention, as it regulates the efficiency of $-$1 programmed ribosomal frameshifting ($-$1 PRF), a mechanism that is essential for viral protein synthesis. The pseudoknot…
Lipid membranes and membrane deformations are a long-standing area of research in soft matter and biophysics. Computer simulations have complemented analytical and experimental approaches as one of the pillars in the field. However, setting…
The crossword-like patterns of tiles in Scrabble form connected graphs of occupied sites on a square lattice. We find the most structureless description that reproduces means and covariances observed in real Scrabble games by adapting a…
Mesoscopic fluctuations reveal stochastic dynamics of molecules in both inanimate and living matter. We investigate how small-number fluctuations shape the collective dynamics of molecular motors using motile cilia as model system. We…
Primates exhibit a robust deviation from canonical allometric scaling: at fixed body mass, their lifespans exceed those of non-primate mammals by factors of two to three. A rhesus macaque (8 kg) lives 25-40 years, whereas a cat of similar…
A pygmy shrew (\textit{Suncus etruscus}, ${\approx}2$\,g) sustains a resting heart rate near $1{,}000$\,beats\,min$^{-1}$ and dies within two years; an African elephant (${\approx}4{,}000$\,kg) beats at $28$\,beats\,min$^{-1}$ and lives…
Arabidopsis roots show oscillatory growth patterns on homogeneous agar surfaces, whereas other plants, such as maize, do not. Although several explanations have been proposed, a simple and general model that makes testable predictions…
Accurately linking microscopic energy deposition from ionizing radiation to emergent biological outcomes remains a central challenge in radiobiological modelling, particularly when stochastic damage induction, cell-cycle dynamics, and…
Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…
This study presents a versatile ontology and a useful codification scheme for describing all kinds of engineered living materials (ELMs). The different components of the ontology, namely: families according to the taxonomy for ELMs,…
The ability to fly through openings in vegetation allows insects like bees to access otherwise unreachable food sources. The specific visual strategies employed by flying insects during aperture negotiation tasks remain unknown. In this…