Biological Physics
Biological systems are homochiral, raising the question of how a racemic mixture of prebiotically synthesized biomolecules could attain a homochiral state at the network level. Based on our recent results, we aim to address a related…
Homochirality is a signature of life on Earth yet its origins remain an unsolved puzzle. Achieving homochirality is essential for a high-yielding prebiotic network capable of producing functional polymers like ribonucleic acid (RNA) and…
Cellular development follows a stochastic yet rule-governed trajectory, though the underlying principles remain elusive. Here, we propose that cellular development follows paths of least action, aligning with foundational physical laws that…
Cell migration, which is strictly regulated by intracellular and extracellular cues, is crucial for normal physiological processes and the progression of certain diseases. However, there is a lack of an efficient approach to analyze…
A leading theory for the biological effects of low-intensity magnetic fields is the spin-chemical Radical Pair Mechanism. This mechanism is best described by the master equation for the density matrix of an open quantum system, which…
Developing physics-based models for molecular simulation requires fitting many unknown parameters to diverse experimental datasets. Traditionally, this process is piecemeal and difficult to reproduce, leading to a fragmented landscape of…
Recent studies have suggested that the Nuclear Pore Complex (NPC) plays a significant role in mechanotransduction. When a force is exerted, the NPC's diameter widens, leading to an increased molecular flux into the nucleus. In this study,…
During development and under normal physiological conditions, biological tissues are continuously subjected to substantial mechanical stresses. In response to large deformations cells in a tissue must undergo multicellular rearrangements in…
The plasmodium of the true slime mold Physarum polycephalum serves as a platform to study information processing in non-equilibrium active matter, showing complex oscillations and computation despite its simple morphology. Past experiments…
Relationships between plants and insects vitally underpin the health of global ecosystems and food production. Through co-evolution, insects have acquired a variety of senses in response to the emergence of floral cues such as scent, colour…
To investigate the anisotropic properties of biomaterials, two distinct classes are considered: polymer-based (e.g., cellulose in plants) and crystalline-based (e.g., enamel in teeth), each demonstrating distinct structural and functional…
While hydrodynamic coupling has long been considered essential for synchronisation of eukaryotic flagella, recent experiments on the unicellular biflagellate model organism {\it Chlamydomonas} demonstrate that -- at the single cell level --…
The exploration of brain networks has reached an important milestone as relatively large and reliable information has been gathered for connectomes of different species. Analyses of connectome data sets reveal that the structural length and…
This systematic review outlines pivotal advancements in deep learning-driven protein structure prediction and design, focusing on four core models-AlphaFold, RoseTTAFold, RFDiffusion, and ProteinMPNN-developed by 2024 Nobel Laureates in…
Nonlinearity and non-Hermiticity, for example due to environmental gain-loss processes, are a common occurrence throughout numerous areas of science and lie at the root of many remarkable phenomena. For the latter, parity-time-reflection…
Biological cells exhibit a hierarchical spatial organization, where various compartments harbor condensates that form by phase separation. Cells can control the emergence of these condensates by affecting compartment size, the amount of the…
We study the SIRS epidemic model, both analytically and on a square lattice. The analytic model has two stable solutions, post outbreak/epidemic (no infected, $I=0$) and the endemic state (constant number of infected: $I>0$). When the model…
Outdoor built environments can be designed to enhance thermal comfort, yet the relationship between the two is often assessed in whole-body terms, overlooking the asymmetric nature of thermal interactions between the human body and its…
Blood rheology and microcirculation are strongly influenced by red blood cell (RBC) aggregation. The aggregability of RBCs can vary significantly due to factors such as their mechanical and membrane surface properties, which are affected by…
We analyze critical time series of the order parameter generated with active to inactive phase transitions of spreading dynamics running on the top of heterogeneous networks. Different activation mechanisms that govern the dynamics near the…