We study the spin-dependent quark distributions at large transverse momentum. We derive their transverse momentum behaviors in the collinear factorization approach in this region. We further calculate the angular distribution of the Drell-Yan lepton pair production with polarized beams and present the results in terms of the collinear twist-three quark-gluon correlation functions. In the intermediate transverse momentum region, we find that the two pproaches: the collinear factorization and the transverse momentum dependent factorization approaches are consistent in the description of the lepton pair angular distributions.