English

Toward AI-Ready Medical Imaging Data

Other Quantitative Biology 2025-12-04 v1

Abstract

Medical imaging data plays a vital role in disease diagnosis, monitoring, and clinical research discovery. Biomedical data managers and clinical researchers must navigate a complex landscape of medical imaging infrastructure, input/output tools and data reliability workflow configurations taking months to operationalize. While standard formats exist for medical imaging data, standard operating procedures (SOPs) for data management are lacking. These data management SOPs are key for developing Findable, Accessible, Interoperable, and Reusable (FAIR) data, a prerequisite for AI-ready datasets. The National Institutes of Health (NIH) Bridge to Artificial Intelligence (Bridge2AI) Standards Working Group members and domain-expert stakeholders from the Bridge2AI Grand Challenges teams developed data management SOPs for the Digital Imaging and Communications in Medicine (DICOM) format. We describe novel SOPs applying to both static and cutting edge video imaging modalities. We emphasize steps required for centralized data aggregation, validation, and de-identification, including a review of new defacing methods for facial DICOM scans, anticipating adversarial AI/ML data re-identification methods. Data management vignettes based on Bridge2AI datasets include example parameters for efficient capture of a wide modality spectrum, including datasets from new ophthalmology retinal scans DICOM modalities.

Keywords

Cite

@article{arxiv.2512.03541,
  title  = {Toward AI-Ready Medical Imaging Data},
  author = {Milen Nikolov and Edilberto Amorim and J Harry Caufield and Nayoon Gim and Nomi L Harris and Jared Houghtaling and Xiang Li and Danielle Morrison and Anaïs Rameau and Jamie Shaffer and Hari Trivedi and Monica C Munoz-Torres},
  journal= {arXiv preprint arXiv:2512.03541},
  year   = {2025}
}
R2 v1 2026-07-01T08:07:17.731Z