We present a theoretical analysis that associates the resonances of extraordinary acoustic Raman (EAR) spectroscopy [Wheaton et al., Nat Photon 9, 68 (2015)] with the collective modes of proteins. The theory uses the anisotropic elastic network model to find the protein acoustic modes, and calculates Raman intensity by treating the protein as a polarizable ellipsoid. Reasonable agreement is found between EAR spectra and our theory. Protein acoustic modes have been extensively studied theoretically to assess the role they play in protein function; this result suggests EAR as a new experimental tool for studies of protein acoustic modes.
@article{arxiv.1608.01279,
title = {Theory for the Acoustic Raman Modes of Proteins},
author = {Timothy DeWolf and Reuven Gordon},
journal= {arXiv preprint arXiv:1608.01279},
year = {2016}
}
Comments
5 pages; 2 figures (2 distinct figure floats); 1 table; has supporting info that needs included