This paper explores the adaptation and application of i-TED Compton imagers for real-time dosimetry in Boron Neutron Capture Therapy (BNCT). The i-TED array, previously utilized in nuclear astrophysics experiments at CERN, is being optimized for detecting and imaging 478 keV gamma-rays, critical for accurate BNCT dosimetry. Detailed Monte Carlo simulations were used to optimize the i-TED detector configuration and enhance its performance in the challenging radiation environment typical of BNCT. Additionally, advanced 3D image reconstruction algorithms, including a combination of back-projection and List-Mode Maximum Likelihood Expectation Maximization (LM-MLEM), are implemented and validated through simulations. Preliminary experimental tests at the Institut Laue-Langevin (ILL) demonstrate the potential of i-TED in a clinical setting, with ongoing experiments focusing on improving imaging capabilities in realistic BNCT conditions.
@article{arxiv.2409.10107,
title = {The i-TED Compton Camera Array for real-time boron imaging and determination during treatments in Boron Neutron Capture Therapy},
author = {Pablo Torres-Sánchez and Jorge Lerendegui-Marco and Javier Balibrea-Correa and Victor Babiano-Suárez and Bernardo Gameiro and Ion Ladarescu and Patricia Álvarez-Rodríguez and Jean-Michel Daugas and Ulli Koester and Caterina Michelagnoli and Maria Pedrosa-Rivera and Ignacio Porras and Maria José Ruiz-Magaña and Carmen Ruiz-Ruiz and César Domingo-Pardo},
journal= {arXiv preprint arXiv:2409.10107},
year = {2024}
}
Comments
9 pages, 7 figures, submitted to the Special Issue of Applied Radiation and Isotopes associated to the 20th International Congress on Neutron Capture Therapy (20th ICNCT)