English

Simple models of proteins with repulsive non-native contacts

Soft Condensed Matter 2009-10-31 v1 Statistical Mechanics q-bio

Abstract

The Go model is extended to the case when the non-native contact energies may be either attractive or repulsive. The folding temperature is found to increase with the energy of non-native contacts. The repulsive non-native contact energies may lead to folding at T=0 for some two-dimensional sequences and to reduction in complexity of disconnectivity graphs for local energy minima.

Keywords

Cite

@article{arxiv.cond-mat/9904421,
  title  = {Simple models of proteins with repulsive non-native contacts},
  author = {Mai Suan Li and Marek Cieplak},
  journal= {arXiv preprint arXiv:cond-mat/9904421},
  year   = {2009}
}

Comments

6 pages, latex, 9 figures, submitted to Phys. Rev. E