English

Kinetic non-optimality and vibrational stability of proteins

Statistical Mechanics 2007-05-23 v1 Soft Condensed Matter q-bio

Abstract

Scaling of folding times in Go models of proteins and of decoy structures with the Lennard-Jones potentials in the native contacts reveal %robust power law trends when studied under optimal folding conditions. The power law exponent depends on the type of native geometry. Its value indicates lack of kinetic optimality in the model proteins. In proteins, mechanical and thermodynamic stabilities are correlated.

Keywords

Cite

@article{arxiv.cond-mat/0102316,
  title  = {Kinetic non-optimality and vibrational stability of proteins},
  author = {Marek Cieplak and Trinh Xuan Hoang},
  journal= {arXiv preprint arXiv:cond-mat/0102316},
  year   = {2007}
}

Comments

REVTex, Proteins: Function, Structure and Genetics - in press