Shot noise limited high speed stimulated Raman microscopy
Optics
2019-05-29 v1 Biological Physics
Abstract
We report a shot noise limited high speed stimulated Raman microscopy platform allowing to acquire molecular vibrational spectra over \SI{200}{\per \cm} in \SI{12}{\micro \second} at a scan rate of 40kHz. Using spectral focusing together with optimized acousto-optics programmable dispersive filters the designed low noise imaging platform performs chemical imaging of dynamical processes such as Mannitol crystal hydratation and reaches a signal to noise ratio sufficient to perform label free histological imaging on frozen human colon tissue slides.
Keywords
Cite
@article{arxiv.1905.11953,
title = {Shot noise limited high speed stimulated Raman microscopy},
author = {Xavier Audier and Nicolas Forget and Hervé Rigneault},
journal= {arXiv preprint arXiv:1905.11953},
year = {2019}
}