English

Remarks on Feedforward Circuits, Adaptation, and Pulse Memory

Quantitative Methods 2009-06-07 v2

Abstract

This note studies feedforward circuits as models for perfect adaptation to step signals in biological systems. A global convergence theorem is proved in a general framework, which includes examples from the literature as particular cases. A notable aspect of these circuits is that they do not adapt to pulse signals, because they display a memory phenomenon. Estimates are given of the magnitude of this effect.

Keywords

Cite

@article{arxiv.0812.0622,
  title  = {Remarks on Feedforward Circuits, Adaptation, and Pulse Memory},
  author = {Eduardo D. Sontag},
  journal= {arXiv preprint arXiv:0812.0622},
  year   = {2009}
}

Comments

Updates version 1; added many references, simulations, examples, and also more comments on approximate adaptation

R2 v1 2026-06-21T11:47:46.195Z