Reduction to the Simplest - The Complexity of Minimalistic Heteropolymer Models
Soft Condensed Matter
2007-10-25 v1 Biological Physics
Abstract
Simple coarse-grained hydrophobic-polar models for heteropolymers as the lattice HP and the off-lattice AB model allow a general classification of characteristic behaviors for hydrophobic-core based tertiary folding. The strongly reduced computational efforts enable one to reveal systematically the thermodynamic properties of comparatively long sequences in a wide temperature range of conformational activity. Based on a suitable cooperativity parameter, characteristic folding channels and free-energy landscapes, which have strong similarities with realistic folding paths, can be analysed.
Keywords
Cite
@article{arxiv.0710.4353,
title = {Reduction to the Simplest - The Complexity of Minimalistic Heteropolymer Models},
author = {Michael Bachmann and Wolfhard Janke},
journal= {arXiv preprint arXiv:0710.4353},
year = {2007}
}
Comments
3 pages, 1 figure