Protein crystallization in confined geometries

S. Tanaka; S. U. Egelhaaf; W. C. K. Poon

Protein crystallization in confined geometries

Soft Condensed Matter 2007-05-23 v1 Biomolecules

Authors: S. Tanaka , S. U. Egelhaaf , W. C. K. Poon

Abstract

We studied the crystallization of a globular protein, lysozyme, in the cubic phase of the lipid monoolein. The solubility of lysozyme in salt solution decreased by a factor of $\sim 4$ when confined in cubic phase. Calculations and Monte Carlo simulations show that this can be explained by the {\it confinement} of lysozyme molecules to the narrow water cells in the cubic phase.

Keywords

protein crystallization confined geometry lysozyme monoolein Monte Carlo simulation

Cite

@article{arxiv.cond-mat/0309373,
  title  = {Protein crystallization in confined geometries},
  author = {S. Tanaka and S. U. Egelhaaf and W. C. K. Poon},
  journal= {arXiv preprint arXiv:cond-mat/0309373},
  year   = {2007}
}

Comments

4 pages, 5 figures

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