Point-primitive, line-transitive generalised quadrangles of holomorph type

Let $G$ be a group of collineations of a finite thick generalised quadrangle $\Gamma$. Suppose that $G$ acts primitively on the point set $\mathcal{P}$ of $\Gamma$, and transitively on the lines of $\Gamma$. We show that the primitive action of $G$ on $\mathcal{P}$ cannot be of holomorph simple or holomorph compound type. In joint work with Glasby, we have previously classified the examples $\Gamma$ for which the action of $G$ on $\mathcal{P}$ is of affine type. The problem of classifying generalised quadrangles with a point-primitive, line-transitive collineation group is therefore reduced to the case where there is a unique minimal normal subgroup $M$ and $M$ is non-Abelian.