Orientational correlations in confined DNA
Soft Condensed Matter
2015-06-03 v3 Biological Physics
Abstract
We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.
Keywords
Cite
@article{arxiv.1201.2961,
title = {Orientational correlations in confined DNA},
author = {E. Werner and F. Persson and F. Westerlund and J. O. Tegenfeldt and B. Mehlig},
journal= {arXiv preprint arXiv:1201.2961},
year = {2015}
}
Comments
Revised version including supplemental material, 7 pages, 8 figures