English

Non-affine mechanics of entangled networks inspired by intermediate filaments

Biological Physics 2023-08-16 v3 Materials Science Adaptation and Self-Organizing Systems

Abstract

Inspired by massive intermediate filament (IF) reorganization in superstretched epithelia, we examine computationally the principles controlling the mechanics of a set of entangled filaments whose ends slide on the cell boundary. We identify an entanglement metric and threshold beyond which random loose networks respond non-affinely and nonlinearly to stretch by self-organizing into structurally optimal star-shaped configurations. A simple model connecting cellular and filament strains links emergent mechanics to cell geometry, network topology, and filament mechanics. We identify a safety net mechanism in IF networks and provide a framework to harness entanglement in soft fibrous materials.

Keywords

Cite

@article{arxiv.2206.04043,
  title  = {Non-affine mechanics of entangled networks inspired by intermediate filaments},
  author = {M. Pensalfini and T. Golde and X. Trepat and M. Arroyo},
  journal= {arXiv preprint arXiv:2206.04043},
  year   = {2023}
}

Comments

23 pages, 16 figures; expanded discussion of non-affinity, added supplementary data on interaction with frictional background at fast loading rates, modified title, results unchanged