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Natural site-directed mutagenesis might exist in eukaryotic cells

Subcellular Processes 2016-04-19 v2

Abstract

Site-directed mutagenesis refers to a man-made molecular biology method that is used to make genetic alterations in the DNA sequence of a gene of interest. But based on our recently published experimental findings, we propose that natural site-directed mutagenesis might exist in the eukaryotic cells, which is triggered by harmful agents and co-directed by special transcription hotspots and mutation-contained intranuclear primers.

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Cite

@article{arxiv.1603.06538,
  title  = {Natural site-directed mutagenesis might exist in eukaryotic cells},
  author = {Gao-De Li},
  journal= {arXiv preprint arXiv:1603.06538},
  year   = {2016}
}

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5 pages