Modeling the hallmarks of avascular tumors
Populations and Evolution
2024-02-05 v1 Dynamical Systems
Abstract
We present a stochastic computational model of avascular tumors, emphasizing the detailed implementation of the first four so-called hallmarks of cancer: self-sufficiency in growth factors, resistance to growth inhibitors, avoidance of apoptosis, and unlimited growth potential. Our goal is to provide a foundational understanding of the first steps of cancer malignancy while addressing modeling uncertainties, thus bringing us closer to a first-principles grasp of this process. Preliminary numerical simulations illustrate the comprehensiveness of our perspective.
Keywords
Cite
@article{arxiv.2402.01305,
title = {Modeling the hallmarks of avascular tumors},
author = {Erik Blom and Stefan Engblom and Gesina Menz},
journal= {arXiv preprint arXiv:2402.01305},
year = {2024}
}
Comments
9 pages, 2 figures; submitted to ENUMATH23 Proceedings