This chapter gives a synopsis of recent approaches to model and analyse the evolution of microbial populations under selection. The first part reviews two population genetic models of Lenski's long-term evolution experiment with Escherichia coli, where models aim at explaining the observed curve of the evolution of the mean fitness. The second part describes a model of a host-pathogen system where the population of pathogenes experiences balancing selection, migration, and mutation, as motivated by observations of the genetic diversity of HCMV (the human cytomegalovirus) across hosts.
@article{arxiv.2004.01011,
title = {Microbial populations under selection},
author = {Ellen Baake and Anton Wakolbinger},
journal= {arXiv preprint arXiv:2004.01011},
year = {2021}
}
Comments
to appear in: Probabilistic Structures in Evolution, E.~Baake and A.~Wakolbinger (eds.), EMS Publishing House, Zurich